Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™

epithelial Sodium Channel alpha antibody

Boster Bio Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™ catalog # A01413-1. Tested in IF, ICC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A01413-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IF, ICC, WB

Customers Who Bought This Also Bought

Product Name

Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™

View all epithelial Sodium Channel alpha Antibodies

SKU/Catalog Number

A01413-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™ catalog # A01413-1. Tested in IF, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01413-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SCNN1A, which shares 83.3% amino acid (aa) sequence identity with both mouse and rat SCNN1A.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01413-1 is reactive to SCNN1A in Human

Applications

A01413-1 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

76 kDa

Calculated molecular weight

75.704kDa

Background of epithelial Sodium Channel alpha

The SCNN1A gene encodes the alpha subunit of the epithelial sodium channel (ENaC), a constitutively active channel that allows the flow of sodium ions from the lumen into epithelial cells across the apical cell membrane. The ENaC channel, which is regulated by the renin-angiotensin-aldosterone system, has a central role in the regulation of extracellular fluid volume and blood pressure. The other subunits are encoded by the beta (SCNN1B), gamma (SCNN1G), and delta (SCNN1D) genes. This SCNN1A gene is mapped to 12p13.31. Mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunocytochemistry/ Immunofluorescence, 2μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For SCNN1A (Source: Uniprot.org, NCBI)

Gene Name

SCNN1A

Full Name

Amiloride-sensitive sodium channel subunit alpha

Weight

75.704kDa

Superfamily

amiloride-sensitive sodium channel (TC 1.A.6) family

Alternative Names

alpha ENaC-2; alpha-ENaC; alpha-NaCH; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha 2; amiloride-sensitive sodium channel subunit alpha; BESC2; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; FLJ21883; nasal epithelial sodium channel alpha subunit; Nonvoltage-gated sodium channel 1 subunit alpha; SCNEA; SCNN1; sodium channel, nonvoltage-gated 1 alpha SCNN1A BESC2, ENaCa, ENaCalpha, LIDLS3, SCNEA, SCNN1 sodium channel epithelial 1 subunit alpha amiloride-sensitive sodium channel subunit alpha|alpha ENaC-2|alpha-ENaC|alpha-NaCH|amiloride-sensitive epithelial sodium channel alpha subunit|amiloride-sensitive sodium channel subunit alpha 2|epithelial Na(+) channel subunit alpha|nasal epithelial sodium channel alpha subunit|nonvoltage-gated sodium channel 1 subunit alpha|sodium channel epithelial 1 alpha subunit|sodium channel, non voltage gated 1 alpha subunit|sodium channel, non-voltage-gated 1 alpha|sodium channel, nonvoltage-gated 1 alpha

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SCNN1A, check out the SCNN1A Infographic

SCNN1A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SCNN1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for A01413-1

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

1 Customer Q&As for Anti-epithelial Sodium Channel alpha/SCNN1A Antibody Picoband™

Question

We are currently using anti-epithelial Sodium Channel alpha/SCNN1A antibody A01413-1 for human tissue, and we are satisfied with the IF results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2019-12-03

Answer

The anti-epithelial Sodium Channel alpha/SCNN1A antibody (A01413-1) has not been validated for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-12-03

Order DetailsPrice
A01413-1

100μg

$370
A01413-1-10ug

10μg sample (liquid)

$99
A01413-1-Biotin

100 μg Biotin conjugated

$570
A01413-1-Cy3

100 μg Cy3 conjugated

$570
A01413-1-Dylight488

100 μg Dylight488 conjugated

$570
A01413-1-Dylight550

100 μg Dylight550 conjugated

$570
A01413-1-Dylight594

100 μg Dylight594 conjugated

$570
A01413-1-FITC

100 μg FITC conjugated

$570
A01413-1-HRP

100 μg HRP conjugated

$570
A01413-1-APC

100 μg APC conjugated

$670
A01413-1-PE

100 μg PE conjugated

$670
A01413-1-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
A01413-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.