Anti-SCP3/SYCP3 Antibody

SCP3/SYCP3 antibody

Boster Bio Anti-SCP3/SYCP3 Antibody catalog # RP1035. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: RP1035
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-SCP3/SYCP3 Antibody

View all SCP3/SYCP3 Antibodies

SKU/Catalog Number

RP1035

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SCP3/SYCP3 Antibody catalog # RP1035. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SCP3/SYCP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1035)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1035 is reactive to Sycp3 in Human

Applications

RP1035 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

28 kDa

Calculated molecular weight

29.347kDa

Background of SCP3/SYCP3

SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For Sycp3 (Source: Uniprot.org, NCBI)

Gene Name

Sycp3

Full Name

Synaptonemal complex protein 3

Weight

29.347kDa

Superfamily

XLR/SYCP3 family

Alternative Names

SCP3; COR1; MGC71888; SCP3 chromosome 3 open reading frame 8; SCP3 COR1; SCP3; SCP-3; SYCP3; synaptonemal complex protein 3 Sycp3|Co, Cor1, Sc, Scp3|synaptonemal complex protein 3|synaptonemal complex protein 3|SCP-3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Sycp3, check out the Sycp3 Infographic

Sycp3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Sycp3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-SCP3/SYCP3 Antibody

Question

Does anti-SCP3/SYCP3 antibody RP1035 work for WB with testis?

Verified Customer

Verified customer

Asked: 2020-03-04

Answer

According to the expression profile of testis, SYCP3 is highly expressed in testis. So, it is likely that anti-SCP3/SYCP3 antibody RP1035 will work for WB with testis.

Boster Scientific Support

Answered: 2020-03-04

Question

We are currently using anti-SCP3/SYCP3 antibody RP1035 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on zebrafish tissues as well?

A. Thomas

Verified customer

Asked: 2020-02-10

Answer

The anti-SCP3/SYCP3 antibody (RP1035) has not been tested for cross reactivity specifically with zebrafish tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-02-10

Question

Our lab want to know about to test anti-SCP3/SYCP3 antibody RP1035 on human testis for research purposes, then I may be interested in using anti-SCP3/SYCP3 antibody RP1035 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

C. Anderson

Verified customer

Asked: 2016-07-25

Answer

The products we sell, including anti-SCP3/SYCP3 antibody RP1035, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2016-07-25

Order DetailsPrice
RP1035

100μg

$370
RP1035-10ug

10μg sample (liquid)

$99
RP1035-Biotin

100 μg Biotin conjugated

$570
RP1035-Cy3

100 μg Cy3 conjugated

$570
RP1035-Dylight488

100 μg Dylight488 conjugated

$570
RP1035-Dylight550

100 μg Dylight550 conjugated

$570
RP1035-Dylight594

100 μg Dylight594 conjugated

$570
RP1035-FITC

100 μg FITC conjugated

$570
RP1035-HRP

100 μg HRP conjugated

$570
RP1035-APC

100 μg APC conjugated

$670
RP1035-PE

100 μg PE conjugated

$670
RP1035-carrier-free

Carrier Free

$370

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RP1035
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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