Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™

Serpin A1/alpha 1-Antitrypsin antibody

Boster Bio Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™ catalog # PB9354. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: PB9354
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™

View all Serpin A1/alpha 1-Antitrypsin Antibodies

SKU/Catalog Number

PB9354

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™ catalog # PB9354. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9354)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived rat SERPINA1 recombinant protein (Position: K211-R411). Rat SERPINA1 shares 66% amino acid (aa) sequence identity with human SERPINA1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9354 is reactive to SERPINA1 in Mouse, Rat

Applications

PB9354 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

53 kDa

Calculated molecular weight

46.737kDa

Background of Serpin A1/alpha 1-Antitrypsin

SERPINA1 is also known as PI, A1A or AAT. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For SERPINA1 (Source: Uniprot.org, NCBI)

Gene Name

SERPINA1

Full Name

Alpha-1-antitrypsin

Weight

46.737kDa

Superfamily

serpin family

Alternative Names

A1A; A1AT; AATMGC23330; alpha 1-Antitrypsin; alpha 1-Proteinase Inhibitor; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; alpha-1-antitrypsin; antitrypsin), member 1; member 1; PIMGC9222; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; serine (or cysteine) proteinase inhibitor, clade A, member 1; Serpin A1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) SERPINA1 A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF serpin family A member 1 alpha-1-antitrypsin|alpha-1 antitrypsin|alpha-1 protease inhibitor|alpha-1-antiproteinase|alpha-1-antitrypsin short transcript variant 1C4|alpha-1-antitrypsin short transcript variant 1C5|epididymis secretory sperm binding protein|protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin|serine (or cysteine) proteinase inhibitor, clade A, member 1|serpin A1|serpin peptidase inhibitor clade A (alpha-1antiproteinase, antitrypsin) member 1|serpin peptidase inhibitor clade A member 1|serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SERPINA1, check out the SERPINA1 Infographic

SERPINA1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SERPINA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9354 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Label-free proteomic analysis of placental proteins during Toxoplasma gondii infection

Lv X, Gao F, Liu Q, Zhang S, Huang Z, Zhu Y, Zong H, Li Q, Li S. Exp Ther Med. 2018 Feb;15(2):1465-1473. doi: 10.3892/etm.2017.5554. Epub 2017 Nov 23. Clinical and pathological characteristics of IgG4-related interstitial lung disease

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1 Customer Q&As for Anti-alpha 1 Antitrypsin/SERPINA1 Antibody Picoband™

Question

We are currently using anti-alpha 1 antitrypsin/SERPINA1 antibody PB9354 for mouse tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says mouse, rat. Is it likely that the antibody can work on feline tissues as well?

Z. Walker

Verified customer

Asked: 2019-01-30

Answer

The anti-alpha 1 antitrypsin/SERPINA1 antibody (PB9354) has not been tested for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-01-30

Order DetailsPrice
PB9354

100μg

$370
PB9354-10ug

10μg sample (liquid)

$99
PB9354-Biotin

100 μg Biotin conjugated

$570
PB9354-Cy3

100 μg Cy3 conjugated

$570
PB9354-Dylight488

100 μg Dylight488 conjugated

$570
PB9354-Dylight550

100 μg Dylight550 conjugated

$570
PB9354-Dylight594

100 μg Dylight594 conjugated

$570
PB9354-FITC

100 μg FITC conjugated

$570
PB9354-HRP

100 μg HRP conjugated

$570
PB9354-APC

100 μg APC conjugated

$670
PB9354-PE

100 μg PE conjugated

$670
PB9354-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9354
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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