Anti-SHP-2 (Ab-542) PTPN11 Antibody

SHP-2/PTPN11 antibody

Boster Bio Anti-SHP-2 (Ab-542) PTPN11 Antibody (Catalog # A00150). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00150
Size: 100 µl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

Product Name

Anti-SHP-2 (Ab-542) PTPN11 Antibody

View all SHP-2/PTPN11 Antibodies

SKU/Catalog Number

A00150

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-SHP-2 (Ab-542) PTPN11 Antibody (Catalog # A00150). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SHP-2 (Ab-542) PTPN11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00150)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Peptide sequence around aa. 540~544 (H-E-Y-T-N) derived from Human SHP-2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00150 is reactive to PTPN11 in Human, Mouse, Rat

Applications

A00150 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

68.011kDa

Background of SHP-2/PTPN11

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14(9): 3911-3928.
Shi ZQ, et al. (2000) Mol Cell Biol ; 20(5): 1526-1536.
Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A ; 96(17): 9677-9682
Manes S, et al. (1999) Mol Cell Biol ; 19(4): 3125-3135.
Oh ES, et al. (1999) Mol Cell Biol; 19(4): 3205-3215.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 72kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Validation Images & Assay Conditions

Gene/Protein Information For PTPN11 (Source: Uniprot.org, NCBI)

Gene Name

PTPN11

Full Name

Tyrosine-protein phosphatase non-receptor type 11

Weight

68.011kDa

Superfamily

protein-tyrosine phosphatase family

Alternative Names

BPTP3; EC 3.1.3.48; MGC14433; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase-2; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP1D; PTP-1D; PTP2C; PTP-2C; PTP2CNS1; PTPN11; SHP2; SHP-2; SHP2CFC; SHPTP2; SH-PTP2; SH-PTP2Noonan syndrome 1; SH-PTP3; tyrosine-protein phosphatase non-receptor type 11 PTPN11 BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2 protein tyrosine phosphatase non-receptor type 11 tyrosine-protein phosphatase non-receptor type 11|SH2 domain-containing protein tyrosine phosphatase 2|protein-tyrosine phosphatase 1D|protein-tyrosine phosphatase 2C

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PTPN11, check out the PTPN11 Infographic

PTPN11 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PTPN11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00150

100ul

$360

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