Product Info Summary
SKU: | PA1694 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Somatostatin Receptor 2/SSTR2 Antibody
View all Somatostatin R2/SSTR2 Antibodies
SKU/Catalog Number
PA1694
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Somatostatin Receptor 2/SSTR2 Antibody catalog # PA1694. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Somatostatin Receptor 2/SSTR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1694)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Somatostatin Receptor 2, identical to the related rat and mouse sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1694 is reactive to SSTR2 in Human, Mouse, Rat
Applications
PA1694 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
55 kDa
Calculated molecular weight
41.333kDa
Background of Somatostatin R2/SSTR2
SSTR2 (Somatostatin receptor type 2) is a protein that in humans is encoded by the SSTR2 gene. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. Stable SSTR2 transfection of human pancreatic cells, which do not endogenously express SSTR2, inhibits cell proliferation, tumorigenicity, and metastasis. These effects occur as a consequence of an autocrine SSTR2-dependent loop, whereby SSTR2 induces expression of its own ligand, somatostatin.SSTR2 mRNA was variably expressed in all neuroblastoma tumors with a relevant reduction in the more advanced stage.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Rat, Human, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-SSTR2 antibody, PA1694, Western blotting
All lanes: Anti SSTR2 (PA1694) at 0.5ug/ml
WB: Rat Lung Tissue Lysate at 50ug
Predicted bind size: 41KD
Observed bind size: 55KD
Protein Target Info & Infographic
Gene/Protein Information For SSTR2 (Source: Uniprot.org, NCBI)
Gene Name
SSTR2
Full Name
Somatostatin receptor type 2
Weight
41.333kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Smstr2; Somatostatin R2; somatostatin receptor 2; somatostatin receptor type 2; SomatostatinR2; SRIF-1; SS2R; SS-2-R; SS2-R; SST2; SSTR2 SSTR2 somatostatin receptor 2 somatostatin receptor type 2|SRIF-1|SS2R
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SSTR2, check out the SSTR2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SSTR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Somatostatin Receptor 2/SSTR2 Antibody (PA1694)
Hello CJ!
PA1694 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Li M, Wang S, Wang S, Zhang L, Wu D, Yang R, Ji A, Li Y, Wang J. Exp Ther Med. 2017 Aug;14(2):1732-1738. doi: 10.3892/etm.2017.4651. Epub 2017 Jun 22. Occludin downregulation in high glucose is regulated by SSTR2 via the VEGF/NRP1/Akt signaling pa...
Guo Rs, Shi Pd, Zhou J, Chen Yy. Asian Pac J Cancer Prev. 2013;14(7):4071-5. Somatostatin Receptors 3, 4 And 5 Play Important Roles In Gallbladder Cancer.
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-Somatostatin Receptor 2/SSTR2 Antibody
Question
Please see the WB image, lot number and protocol we used for buccal mucosa cell using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2019-08-29
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-08-29
Question
We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for buccal mucosa cell using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2019-06-18
Answer
We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-06-18
Question
We are currently using anti-Somatostatin Receptor 2/SSTR2 antibody PA1694 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on dog tissues as well?
Z. Williams
Verified customer
Asked: 2016-06-22
Answer
The anti-Somatostatin Receptor 2/SSTR2 antibody (PA1694) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2016-06-22