Anti-SorLA SORL1 Monoclonal Antibody

SorLA antibody

Boster Bio Anti-SorLA SORL1 Monoclonal Antibody catalog # M01887. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M01887
Size: 100ul
Reactive Species: Human
Host: Mouse
Application: ELISA, IF, IHC, WB

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Product Name

Anti-SorLA SORL1 Monoclonal Antibody

View all SorLA Antibodies

SKU/Catalog Number

M01887

Size

100ul

Form

Liquid

Description

Boster Bio Anti-SorLA SORL1 Monoclonal Antibody catalog # M01887. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SorLA SORL1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01887)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

3B6B11

Isotype

IgG

Immunogen

Purified recombinant fragment of human SorLA expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01887 is reactive to SORL1 in Human

Applications

M01887 is guaranteed for ELISA, IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

248.426kDa

Background of SorLA

Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
ELISA 1:10000

Validation Images & Assay Conditions

Gene/Protein Information For SORL1 (Source: Uniprot.org, NCBI)

Gene Name

SORL1

Full Name

Sortilin-related receptor

Weight

248.426kDa

Superfamily

VPS10-related sortilin family

Alternative Names

C11orf32; chromosome 11 open reading frame 32; FLJ21930; FLJ39258; gp250; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11; LR11LDLR relative with 11 ligand-binding repeats; LRP9; mosaic protein LR11; SORL1; SorLA; SorLA-1SORLA; sortilin-related receptor; sortilin-related receptor, L(DLR class) A repeats containing; sortilin-related receptor, L(DLR class) A repeats-containing; Sorting protein-related receptor containing LDLR class A repeats SORL1 C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250 sortilin related receptor 1 sortilin-related receptor|LDLR relative with 11 ligand-binding repeats|low-density lipoprotein receptor relative with 11 ligand-binding repeats|mosaic protein LR11|sortilin-related receptor, L(DLR class) A repeats containing|sorting protein-related receptor containing LDLR class A repeats

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SORL1, check out the SORL1 Infographic

SORL1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SORL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01887-100ul

100ul

$380

Free Secondary Antibody

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M01887
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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