Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™

TFF1/pS2 antibody

Boster Bio Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™ catalog # PB9522. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: PB9522
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™

View all TFF1/pS2 Antibodies

SKU/Catalog Number

PB9522

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™ catalog # PB9522. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9522)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human TFF1 recombinant protein (Position: E25-F84). Human TFF1 shares 66.7% and 69% amino acid (aa) sequence identity with mouse and rat TFF1, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9522 is reactive to TFF1 in Human

Applications

PB9522 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

12 kDa

Calculated molecular weight

9.15kDa

Background of TFF1/pS2

TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, -
ELISA , 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For TFF1 (Source: Uniprot.org, NCBI)

Gene Name

TFF1

Full Name

Trefoil factor 1

Weight

9.15kDa

Alternative Names

BCEI; BCEIbreast cancer, estrogen-inducible sequence expressed in; Breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; D21S21; gastrointestinal trefoil protein pS2; hP1.A; HPS2; PNR-2; Polypeptide P1.A; Protein pS2; PS2; TFF1; trefoil factor 1; trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A TFF1 BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 trefoil factor 1|breast cancer estrogen-inducible protein|breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2|polypeptide P1.A|protein pS2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TFF1, check out the TFF1 Infographic

TFF1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TFF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband™

Question

We are currently using anti-Estrogen Inducible Protein pS2/TFF1 antibody PB9522 for human tissue, and we are happy with the ELISA results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on monkey tissues as well?

Verified Customer

Verified customer

Asked: 2019-11-07

Answer

The anti-Estrogen Inducible Protein pS2/TFF1 antibody (PB9522) has not been validated for cross reactivity specifically with monkey tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-11-07

Order DetailsPrice
PB9522

100μg

$370
PB9522-10ug

10μg sample (liquid)

$99
PB9522-Biotin

100 μg Biotin conjugated

$570
PB9522-Cy3

100 μg Cy3 conjugated

$570
PB9522-Dylight488

100 μg Dylight488 conjugated

$570
PB9522-Dylight550

100 μg Dylight550 conjugated

$570
PB9522-Dylight594

100 μg Dylight594 conjugated

$570
PB9522-FITC

100 μg FITC conjugated

$570
PB9522-HRP

100 μg HRP conjugated

$570
PB9522-APC

100 μg APC conjugated

$670
PB9522-PE

100 μg PE conjugated

$670
PB9522-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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