Anti-TIMP4 Monoclonal Antibody

TIMP-4 antibody

Boster Bio Anti-TIMP4 Monoclonal Antibody (Catalog # M07131). Tested in ELISA, IHC applications. This antibody reacts with Human.

Product Info Summary

SKU: M07131
Size: 100ug
Reactive Species: Human
Host: Mouse
Application: ELISA, IHC

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Product Name

Anti-TIMP4 Monoclonal Antibody

View all TIMP-4 Antibodies

SKU/Catalog Number

M07131

Size

100ug

Form

Liquid (sterile filtered)

Description

Boster Bio Anti-TIMP4 Monoclonal Antibody (Catalog # M07131). Tested in ELISA, IHC applications. This antibody reacts with Human.

Storage & Handling

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Cite This Product

Anti-TIMP4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M07131)

Host

Mouse

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

Clonality

Monoclonal

Clone Number

Clone: 9:4-7 IgG2b kappa

Isotype

IgG2b kappa

Immunogen

Anti-TIMP4 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with full length human TIMP4 protein followed by hybridoma development.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M07131 is reactive to TIMP4 in Human

Applications

M07131 is guaranteed for ELISA, IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

25.503kDa

Background of TIMP-4

Tissue inhibitor of metalloproteinase-4 (TIMP-4) is member of the TIMP family of inhibitors of matrix metalloproteinase (MMP) activities. In addition, TIMPs have non-MMP associated functions, including roles in growth promotion, apoptosis, and angiogenesis. All four members of the TIMP gene family form a similar secondary structure due to the formation of six highly conserved disulfide bonds. It has been reported that some TIMPs, TIMP4 included, can bind a tetraspanin in the plasma membrane, initiating an intra-cellular signaling cascade. Elevated levels of TIMP4 have been associated with breast cancer progression and heart disease.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ELISA: 1:20,000 - 1:100,000
IHC: 5-10µg/mL
WB: 1:2,000 to 1:10,000

Validation Images & Assay Conditions

Gene/Protein Information For TIMP4 (Source: Uniprot.org, NCBI)

Gene Name

TIMP4

Full Name

Metalloproteinase inhibitor 4

Weight

25.503kDa

Superfamily

protease inhibitor I35 (TIMP) family

Alternative Names

metalloproteinase inhibitor 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; Tissue inhibitor of metalloproteinases 4 TIMP4 TIMP-4 TIMP metallopeptidase inhibitor 4 metalloproteinase inhibitor 4|tissue inhibitor of metalloproteinase 4|tissue inhibitor of metalloproteinases 4

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TIMP4, check out the TIMP4 Infographic

TIMP4 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TIMP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M07131-100uL

100uL

$612

Free Secondary Antibody

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M07131
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$612.00

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