Anti-Toll-like receptor 5 TLR5 Antibody

TLR5 antibody

Boster Bio Anti-Toll-like receptor 5 TLR5 Antibody (Catalog # A00462). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00462
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IHC-P, WB

Product Name

Anti-Toll-like receptor 5 TLR5 Antibody

View all TLR5 Antibodies

SKU/Catalog Number

A00462

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Toll-like receptor 5 TLR5 Antibody (Catalog # A00462). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

TLR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Toll-like receptor 5 TLR5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00462)

Host

Rabbit

Contents

TLR5 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

TLR5 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TLR5. The immunogen is located within amino acids 450 - 500 of TLR5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

MFN2 antibody is human, mouse and rat reactive. At least three isoforms of MFN2 are known to exist. MFN2 antibody is predicted to not cross-react with MFN1.

Reactive Species

A00462 is reactive to TLR5 in Human, Mouse, Rat

Applications

A00462 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

97.834kDa

Background of TLR5

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-κB, leading to the activation of TNF-α and other cytokines. A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires'disease and demonstrates the importance of TLR5 in the innate immune response.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

TLR5 antibody can be used for detection of TLR5 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For TLR5 (Source: Uniprot.org, NCBI)

Gene Name

TLR5

Full Name

Toll-like receptor 5

Weight

97.834kDa

Superfamily

Toll-like receptor family

Alternative Names

MGC126430; MGC126431; SLEB1FLJ10052; TIL-3; TIL3Toll/interleukin-1 receptor-like protein 3; TLR5; toll-like receptor 5 TLR5 MELIOS, SLE1, SLEB1, TIL3 toll like receptor 5 toll-like receptor 5|systemic lupus erythematosus susceptibility 1|toll/interleukin-1 receptor-like protein 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on TLR5, check out the TLR5 Infographic

TLR5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TLR5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00462-0.1 mg

0.1 mg

$449

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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