|Product Name||Anti-TP53INP2 Antibody|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Cite This Product||Anti-TP53INP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30521)|
|Contents/Buffer||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Immunogen||A peptide derived from human TP53INP2. Immunogen sequence location: 1-50|
|Reactivity||Human, Mouse, Rat|
Assay Dilutions Overview
User need to optimize the dilution ratio for this antibody
Images And Assay Conditions
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of MCF7 cells, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.
Protein Target Info (Source: Uniprot.org)
|Protein Name||Tumor protein p53-inducible nuclear protein 2|
|Alternative Names||Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated protein;Tp53inp2;Dor, Trp53inp2;|
|Subcellular Localization||Cytoplasm, cytosol . Nucleus . Nucleus, PML body . Cytoplasmic vesicle, autophagosome . Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation. .|
|Molecular Weight||24288 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. .|
|Research Areas||Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Intracellular, Oncoproteins/Suppressors, P53 Pathway, Tumor Suppressors
*You can search these to find other products in these research areas.
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