SKU A30521
Size 100ul
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Applications IF, IHC

Overview

Product Name Anti-TP53INP2 Antibody
SKU/Catalog Number A30521
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100ul
Description Anti-TP53INP2 Antibody
Cite This Product Anti-TP53INP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30521)
Host Rabbit
Contents/Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form Liquid
Immunogen A peptide derived from human TP53INP2. Immunogen sequence location: 1-50
Reactivity Human, Mouse, Rat

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
User need to optimize the dilution ratio for this antibody

Images And Assay Conditions

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunofluorescence analysis of MCF7 cells, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id Q8CFU8
Gene Name Tp53inp2
Protein Name Tumor protein p53-inducible nuclear protein 2
Alternative Names Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated protein;Tp53inp2;Dor, Trp53inp2;
Subcellular Localization Cytoplasm, cytosol . Nucleus . Nucleus, PML body . Cytoplasmic vesicle, autophagosome . Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation. .
Molecular Weight 24288 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. .
Research Areas Human, Mouse, Rat

*You can search these to find other products in these research areas.

Other Recommended Resources

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Polyclonal antibody for Tp53inp2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF. Reactive species: Human. Tp53inp2 information: Molecular Weight: 24288 MW; Subcellular Localization: Cytoplasm, cytosol . Nucleus . Nucleus, PML body . Cytoplasmic vesicle, autophagosome . Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
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In stock
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A30521
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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