SKU A30521
Size 100ug/vial
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Applications IF, IHC

Overview

Product Name Anti-TP53INP2 Antibody
SKU/Catalog Number A30521
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100ug/vial
Description Anti-TP53INP2 Antibody
Cite This Product Anti-TP53INP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30521)
Host Rabbit
Contents/Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen A peptide derived from human TP53INP2. Immunogen sequence location: 1-50
Reactivity Human, Mouse, Rat

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
User need to optimize the dilution ratio for this antibody

Images And Assay Conditions

/T/5/T53I2 primary antibodies A30521 IHC testing.jpg

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.

/T/5/T53I2 primary antibodies A30521 IF testing.jpg

Immunofluorescence analysis of MCF7 cells, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id Q8CFU8
Gene Name Tp53inp2
Protein Name Tumor protein p53-inducible nuclear protein 2
Alternative Names Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated protein;Tp53inp2;Dor, Trp53inp2;
Subcellular Localization Cytoplasm, cytosol . Nucleus . Nucleus, PML body . Cytoplasmic vesicle, autophagosome . Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation. .
Molecular Weight 24288 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. .
Research Areas Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Intracellular, Oncoproteins/Suppressors, P53 Pathway, Tumor Suppressors

*You can search these to find other products in these research areas.

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Order Product (A30521)

Promotion:

Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
Option Price
100ug $299
100ug+Free HRP Secondary BA1054 $299
100ug+Free Biotin Secondary BA1003 $299

USD $299

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Troubleshooting

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