Product Info Summary
SKU: | PA1978 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-TRPV3 Antibody
View all Vanilloid R-like 3/TRPV3 Antibodies
SKU/Catalog Number
PA1978
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-TRPV3 Antibody catalog # PA1978. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TRPV3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1978)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human TRPV3, different from the related rat and mouse sequences by four amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1978 is reactive to TRPV3 in Human
Applications
PA1978 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
450 kDa
Calculated molecular weight
90.636kDa
Background of Vanilloid R-like 3/TRPV3
TRPV3 (Transient Receptor Potential Cation Channel Subfamily V Member 3), also known as VRL3, is a human gene encoding the protein of the same name. The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. Peier et al. (2002) localized the TRPV3 gene to a BAC clone mapped to chromosome 17p13. They mapped the mouse gene to chromosome 11B4. Peier et al. (2002) stably expressed mouse Trpv3 in Chinese hamster ovary cells and assayed electrophysiologic activity by whole cell voltage-clamp techniques. They determined that Trpv3 is a cation-permeable channel activated by warm and hot temperatures. Xu et al. (2002) showed that increasing temperature from approximately 22 to 40 degrees Celsius in mammalian cells transfected with human TRPV3 elevated intracellular calcium by activating a nonselective cationic conductance.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Validation Images & Assay Conditions
Click image to see more details
Anti-TRPV3 antibody, PA1978, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: A549 Cell Lysate
Lane 3: MCF-7 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For TRPV3 (Source: Uniprot.org, NCBI)
Gene Name
TRPV3
Full Name
Transient receptor potential cation channel subfamily V member 3
Weight
90.636kDa
Superfamily
transient receptor (TC 1.A.4) family
Alternative Names
transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRPV3; vanilloid receptor 3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; Vanilloid R-like 3; VRL3; VRL-3 TRPV3 FNEPPK2, OLMS, OLMS1, VRL3 transient receptor potential cation channel subfamily V member 3 transient receptor potential cation channel subfamily V member 3|VRL-3|vanilloid receptor-like 3|vanilloid receptor-related osmotically activated channel protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TRPV3, check out the TRPV3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TRPV3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TRPV3 Antibody (PA1978)
Hello CJ!
No publications found for PA1978
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-TRPV3 Antibody
Question
We are currently using anti-TRPV3 antibody PA1978 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on primate tissues as well?
Verified Customer
Verified customer
Asked: 2019-09-23
Answer
The anti-TRPV3 antibody (PA1978) has not been tested for cross reactivity specifically with primate tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-09-23