Anti-uPA Receptor/Plaur Antibody Picoband™

uPAR antibody

Boster Bio Anti-uPA Receptor/Plaur Antibody Picoband™ catalog # A00993-2. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Product Info Summary

SKU: A00993-2
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-uPA Receptor/Plaur Antibody Picoband™

View all uPAR Antibodies

SKU/Catalog Number

A00993-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-uPA Receptor/Plaur Antibody Picoband™ catalog # A00993-2. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-uPA Receptor/Plaur Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00993-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived rat uPA Receptor recombinant protein (Position: L25-R261).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00993-2 is reactive to PLAUR in Mouse, Rat

Applications

A00993-2 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

37 kDa

Calculated molecular weight

36.978kDa

Background of uPAR

PLAUR (PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For PLAUR (Source: Uniprot.org, NCBI)

Gene Name

PLAUR

Full Name

Urokinase plasminogen activator surface receptor

Weight

36.978kDa

Alternative Names

CD87 antigen; CD87; Monocyte activation antigen Mo3; plasminogen activator, urokinase receptor; PLAUR; uPAR; U-PAR; UPARurokinase plasminogen activator surface receptor; u-plasminogen activator receptor form 2; URKRMO3 PLAUR CD87, U-PAR, UPAR, URKR plasminogen activator, urokinase receptor urokinase plasminogen activator surface receptor|monocyte activation antigen Mo3|u-plasminogen activator receptor form 2|urokinase-type plasminogen activator (uPA) receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PLAUR, check out the PLAUR Infographic

PLAUR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PLAUR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00993-2

100μg

$370
A00993-2-10ug

10μg sample (liquid)

$99
A00993-2-Biotin

100 μg Biotin conjugated

$570
A00993-2-Cy3

100 μg Cy3 conjugated

$570
A00993-2-Dylight488

100 μg Dylight488 conjugated

$570
A00993-2-Dylight550

100 μg Dylight550 conjugated

$570
A00993-2-Dylight594

100 μg Dylight594 conjugated

$570
A00993-2-FITC

100 μg FITC conjugated

$570
A00993-2-HRP

100 μg HRP conjugated

$570
A00993-2-APC

100 μg APC conjugated

$670
A00993-2-PE

100 μg PE conjugated

$670
A00993-2-carrier-free

Carrier Free

$370

More conjugates/formats

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A00993-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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