Product Info Summary
SKU: | A00079 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-VHL Antibody
View all Von Hippel Lindau Antibodies
SKU/Catalog Number
A00079
Size
100ul
Form
Liquid
Description
Boster Bio Anti-VHL Antibody catalog # A00079. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-VHL Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00079)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant full length Human IL13.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00079 is reactive to VHL in Human, Mouse, Rat
Applications
A00079 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
24.153kDa
Background of Von Hippel Lindau
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. ATP-Binding Cassette Sub-Family B Member 1 (ABCB1, also named P-glycoprotein) is a plasma membrane-associated multidrug transporter that utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. Unique features of ABCB1 are its very broad substrate specificity and its basal ATPase activity in the absence of transport substrates. Human ABCB1 plays an important role in absorption, distribution, metabolism, excretion and toxicity of pharmacologically relevant drugs. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anti-cancer drugs. This protein also functions as a transporter across the blood-brain barrier.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-VHL Antibody A00079
Western blot (WB) analysis of VHL polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate
Lane2:A549 whole cell lysate
Lane3:Rat brain tissue lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For VHL (Source: Uniprot.org, NCBI)
Gene Name
VHL
Full Name
von Hippel-Lindau disease tumor suppressor
Weight
24.153kDa
Superfamily
VHL family
Alternative Names
elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome; von Hippel-Lindau tumor suppressor VHL HRCA1, RCA11, pVHL, VHL von Hippel-Lindau tumor suppressor von Hippel-Lindau disease tumor suppressor|elongin binding protein|protein G7|von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on VHL, check out the VHL Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for VHL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-VHL Antibody (A00079)
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No publications found for A00079
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