Boster Bio Life Science Blog

  1. Research Spotlight – February 2022

    In this month’s Research Spotlight, we highlight a range of our customers’ publications that investigate complex challenges and the development of life-changing innovations to improve patient health.

    February 2022

    In this month’s Research Spotlight, we highlight a range of our customers’ publications that investigate complex challenges and the development of life-changing innovations to improve patient health.

    Find out how tNIR light treatment might serve as a noninvasive therapeutic alternative for regulating neuronal functions via the improvement of mitochondrial dysfunction mediated by the SIRT1/PGC-1α pathway. In addition, as more studies reveal the key role of circRNAs in cancer, researchers dive deeper into the molecular mechanism of circRNAs in prostate cancer progression.

    In the fields of biomedicine and nanotechnology, scientists also successfully develop [email protected] and HRPS biomimetic nanoparticles that function as high targeting delivery systems for tumor immunotherapy and RA therapy, respectively.

    Scroll down to learn more about the various discoveries and their applications...

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    Research Spotlight – February 2022
  2. Research Spotlight - January 2022

    We’re excited to present our first Research Spotlight edition of 2022, which features the latest scientific innovations from researchers whom Boster has served.

    In this issue, scientists explore the signaling mechanisms of GDF11 during aging, TAF7 during gene expression, OTUD1 in intestinal inflammatory diseases, and the m6Am mRNA in the regulation of obesity.

    January 2022

    We’re excited to present our first Research Spotlight edition of 2022, which features the latest scientific innovations from researchers whom Boster has served.

    In this issue, scientists explore the signaling mechanisms of GDF11 during aging, TAF7 during gene expression, OTUD1 in intestinal inflammatory diseases, and the m6Am mRNA in the regulation of obesity.

    We have also highlighted several studies discussing novel strategies in nanomedicine to help advance modern healthcare, inc...

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    Research Spotlight - January 2022
  3. Research Spotlight - August 2021

    Our August edition of Research Spotlight presents 10 recent publications from scientists whom Boster has served.

    In this month’s edition, research studies delve into the behavioral and cognitive parts of the brain and investigate how various cytokine levels are associated with the progression of neurodegenerative disorders. A comprehensive evaluation of the efficacy and safety of using stem cell therapy for traumatic brain injury is also discussed.

    Researchers explore additional...

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    Research Spotlight - August 2021
  4. Research Spotlight - November 2020

    In our November edition of Research Spotlight, we feature 10 recently published research papers from scientists whom Boster has served.

    This month’s selected research publications investigate how several cells and mediators regulate the development of fibrotic diseases, cancer, inflammatory responses, diabetes, allergy, endometriosis, and anxiety.

    Among the studies, scientists propose the underlying mechanisms of how endothelin receptor antagonists may serve as a therapeutic strategy for fibrotic diseases. The role of PRMT5 in laryngeal tumor carcinogenesis is also explored.

    Discover more details about these new scientific discoveries below.

    Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies

    Authors: Hughes, T.K., Wadsworth, M.H., Gierahn, T.M., Do, T., Weiss, D...
    Journal: Immunity

    High-throughput single-cell RNA-sequencing (scRNA-seq) methodologies enable characterization of complex biological samples by increasing the number of cells that can be profiled contemporaneously. Nevertheless, t

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    Research Spotlight - November 2020
  5. Research Spotlight – June 2020

    The June edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

    This month’s selected research publications investigate several cancers and diseases, including hepatocellular carcinoma, hepatitis B, prostate cancer, ankylosing spondylitis, rheumatoid arthritis, and diabetes.

    Among the studies, scientists propose a prodrug for inflammatory diseases as well as a tumor nanovaccine that utilizes electrostatic interactions. The relationship of depression with inflammation and metabolic dysfunction in addition to ketamine’s potential anti-depressive effects are also explored.

    Scroll down to learn more about these new scientific discoveries.

    A hydrogen peroxide responsive prodrug of Keap1-Nrf2 inhibitor for improving oral absorption and selective activation in inflammatory conditions

    Authors: Lu, M., Zhang, X., Zhao, J., You, Q., & Jiang, Z.
    Journal: Redox Biology

    Transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) and its negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 (Keap1), control the redox and metabolic homeostasis and oxidative stress. Inhibitors of Keap1-Nrf2 interaction are promising in oxidative stress related inflammatory diseases but now hit hurdles. By utilizing...

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    Cited Boster Product(s): Mouse IL-1 Beta ELISA Kit PicoKine™ (EK0394); Mouse IL-6 ELISA Kit PicoKine™ (EK0411); Mouse TNF Alpha ELISA Kit PicoKine™ (EK0527)

    Journal Cover

    The immunoglobulin superfamily member 3 (IGSF3) promotes hepatocellular carcinoma progression through activation of the NF-κB pathway

    Authors: Sheng, P., Zhu, H., Zhang, W., Xu, Y., Peng, W., Sun, J., Gu, M., & Jiang, H.
    Journal: Annals of Translational Medicine

    Background: Patients with hepatocellular carcinoma (HCC) suff

    ...
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    Research Spotlight – June 2020
  6. Research Spotlight – March 2019

    The March edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

    Scientists of this month’s selected research publications investigated several diseases and disorders, such as lung cancer, nasopharynx cancer, alcoholic liver disease, stroke, emphysema, and schizophrenia.

    Among the studies, different cancer treatments are described including preparing chitosan oligosaccharides (COS) as oral nutritional supplements and enhancing dendritic cell-based cancer vaccines with low-dose radiation exposure.

    Scroll down to learn more about these new scientific discoveries.

    Potential Analysis and Preparation of Chitosan Oligosaccharides as Oral Nutritional Supplements of Cancer Adjuvant Therapy

    Authors: Jiang, Z., Li, H., Qiao, J., Yang, Y., Wang, Y., Liu, W., & Han, B.
    Journal: International Journal of Molecular Sciences

    Cancer is considered to have an adverse influence on health around the world. Chitosan, a linear polysaccharide that contains copolymers of β-1-4 linked d-glucosamine and N-acetyl-d-glucosamine un

    ...
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    Research Spotlight – March 2019
  7. Research Spotlight - January 2019

    The January edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

    Scientists of this month’s selected research publications investigate various aspects of several pathways such as the MAPK, Wnt/β-catenin, TGF-β1/Smad3, NF-κB, Akt/mTOR, and AMPK/ULK1 signaling pathways.

    Scroll down to learn more about these new scientific discoveries.

    Luteolin inhibits IL-1β-induced inflammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model

    Authors: Fei, J., Liang, B., Jiang, C., Ni, H., & Wang, L.
    Journal: Biomedicine & Pharmacotherapy

    Osteoarthritis (OA) is a joint disease characterized by inflammation and cartilage degradation. Accumulating evidence has demonstrated that luteolin, a natural flavonoid, has anti-inflammatory and anticatabolic effects. The present study...

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    Cited Boster Product(s): Rat TNF Alpha PicoKine™ ELISA Kit (EK0526); Rat MMP-2 PicoK

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    Research Spotlight - January 2019
  8. Research Spotlight – December 2018

    Our December edition of Research Spotlight features 10 recent research discoveries from scientists whom Boster has served.

    This month’s selected research publications cover disease areas from arthritis to diabetes to Parkinson’s and include studies that examine NK cells and PD-L1 expressions.

    Scroll down to learn more about these new scientific discoveries.

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    Research Spotlight – December 2018