Boster's Picokine™ GDNF ELISA Kit provide high sensitivity low background quantitative detection of GDNF. It is an all-in-one ready to use kit with all components you need for performing colorimetric ELISA assay. Our 4-hour ELISA protocol saves you the trouble of coating the plate. Our kits are thoroughly validated and documented for inter and intra assay variability.
*ELISA bulk discount: 20% off for 4+ kits, 30% off for 20+ kits, applicable only to USA and Canada.
Glial cell line-derived neurotrophic factor(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system. GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. GDNF lies on the short arm of human chromosome 5, at 5p13.1-p13.3 ability to promote dopamine uptake in midbrain cultures.