Picokine™: Performance Guaranteed Best Value ELISA Kit

Boster's Picokine™ TGF alpha ELISA Kit provide high sensitivity low background quantitative detection of TGFA. It is an all-in-one ready to use kit with all components you need for performing colorimetric ELISA assay. Our 4-hour ELISA protocol saves you the trouble of coating the plate. Our kits are thoroughly validated and documented for inter and intra assay variability.

*ELISA bulk discount: 20% off for 4+ kits, 30% off for 20+ kits, applicable only to USA and Canada.

Transforming growth factor alpha(TGF-alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects. TGFalpha stimulates neural cell proliferation in the adult injured brain. Transforming growth factor alpha gene(TGFA) maps to human chromosome 2 close to the breakpoint of the t(2;8) variant translocation in Burkitt lymphoma. Synthetic TGF-alpha was as active as murine epidermal growth factor in binding to the epidermal growth factor receptor and in stimulation of anchorage-dependent and of anchorage-independent growth of normal indicator cells in culture. Synthetic TGF-alpha stimulated plasminogen activator production in A 431 and HeLa cells; the stimulation was similar to that induced by epidermal growth factor. Furthermore, synthetic human TGF-alpha showed similar immunoreactivity when compared with rat TGF-alpha. Thus, the 50-amino acid TGF-alpha is likely to be the bioactive principle produced and secreted by tumor cell lines.

Pack Size:96wells/kit, with removable strips.
Validated Species:Human
Application:ELISA
Sensitivity:<1pg/ml
Sample Type:cell culture supernates, serum, plasma(heparin, EDTA) and human milk.
Availability: Ships next business day
Pack Size:96wells/kit, with removable strips.
Validated Species:Monkey
Application:ELISA
Sensitivity:<1pg/ml
Sample Type:cell culture supernates, serum, plasma(heparin, EDTA) and monkey primate milk.
Availability: Ships next business day
Pack Size:96wells/kit, with removable strips.
Validated Species:Rabbit
Application:ELISA
Sensitivity:<1pg/ml
Sample Type:cell culture supernates, serum, plasma(heparin, EDTA) and rabbit milk.
Availability: Ships next business day
Pack Size:96wells/kit, with removable strips.
Validated Species:Equine
Application:ELISA
Sensitivity:<1pg/ml
Sample Type:cell culture supernates, serum, plasma(heparin, EDTA) and horse equine milk.
Availability: Ships next business day
Pack Size:96wells/kit, with removable strips.
Validated Species:Pig
Application:ELISA
Sensitivity:<1pg/ml
Sample Type:cell culture supernates, serum, plasma(heparin, EDTA) and Pig porcine milk.
Availability: Ships next business day
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