PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein
|Size||2ug, 10ug, 1mg|
|Product Name||PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein|
|Size||2ug, 10ug, 1mg|
|Storage & Handling||Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.|
|Description||PEA15 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 130 amino acids (1-130 a.a.) and having a molecular mass of 15kDa.
The PEA15 is purified by proprietary chromatographic techniques.
|Cite This Product||PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ15121)|
Protein Target Info (Source: Uniprot.org)
|Protein Name||Astrocytic phosphoprotein PEA-15|
|Tissue Specificity||Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.|
|Alternative Names||Astrocytic phosphoprotein PEA-15;15 kDa phosphoprotein enriched in astrocytes;Phosphoprotein enriched in diabetes;PED;PEA15;|
|Subcellular Localization||Cytoplasm. Associated with microtubules.|
|Protein Function||Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.|
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
Q: Is this protein biologically active?A: If there is no biological activity section mentioned in our data sheet it means that we have not assessed the bio-functionality of the protein to date. So, we cannot guarantee that the protein is biologically active.