PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein

SKU PROTQ15121
Size 2ug, 10ug, 1mg
Applications Cell Culture

Overview

Product Name PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein
SKU/Catalog Number PROTQ15121
Size 2ug, 10ug, 1mg
Storage & Handling Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Description PEA15 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 130 amino acids (1-130 a.a.) and having a molecular mass of 15kDa.
The PEA15 is purified by proprietary chromatographic techniques.
Cite This Product PEA15 Phosphoprotein Enriched in Astrocytes 15 Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ15121)
Applications Cell Culture

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id Q15121
Gene Name PEA15
Protein Name Astrocytic phosphoprotein PEA-15
Tissue Specificity Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose- producing tissues. Higher levels of expression are found in tissues from individuals with type 2 diabetes than in controls.
Alternative Names Astrocytic phosphoprotein PEA-15;15 kDa phosphoprotein enriched in astrocytes;Phosphoprotein enriched in diabetes;PED;PEA15;
Subcellular Localization Cytoplasm. Associated with microtubules.

Ontology

Protein Function Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.

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PROTQ15121
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Customer Q&As

  • Q: Is this protein biologically active?
    A: If there is no biological activity section mentioned in our data sheet it means that we have not assessed the bio-functionality of the protein to date. So, we cannot guarantee that the protein is biologically active.
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