Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody

Product Name

Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody

View all PLAGL2 Antibodies

SKU/Catalog Number

A09816

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody (Catalog # A09816). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

PLAGL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Zinc finger protein PLAGL2 PLAGL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09816)

Host

Rabbit

Contents

PLAGL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2. The immunogen is located within amino acids 40 - 90 of PLAGL2.

Cross-reactivity

At least two isoforms are known to exist.

Reactive Species

A09816 is reactive to PLAGL2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

54.6 kDa

Background of PLAGL2

The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A09816 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information PLAGL2

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