Recombinant Human ENA-78 (CXCL5) (5-78 a.a.) Protein

ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues.

Product Info Summary

SKU: PROTP42830-2
Size: Various Sizes
Origin Species: Mouse
Source: E. Coli
Application: Cell Culture

Product Name

Recombinant Human ENA-78 (CXCL5) (5-78 a.a.) Protein

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SKU/Catalog Number

PROTP42830-2

Size

Various Sizes

Form

Solid; white powder or thin/invisible film

Description

ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant human ENA-78 is an 8.0 kDa protein consisting of 74 amino acid residues.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Recombinant Human ENA-78 (CXCL5) (5-78 a.a.) Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP42830-2)

Formulation

Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.

Predicted MW

11.972kDa

Biological Activity And Protein Authenticity

Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration of 5.0-10.0 ng/ml.

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Validation Images & Assay Conditions

Gene/Protein Information For CXCL5 (Source: Uniprot.Org, NCBI)

Uniprot ID

P42830

Gene ID

6374

Gene Name

CXCL5

Full Name

C-X-C motif chemokine 5

Weight

11.972kDa

Superfamily

intercrine alpha (chemokine CxC) family

Alternative Names

LIX CXCL5 ENA-78, SCYB5 C-X-C motif chemokine ligand 5 C-X-C motif chemokine 5|chemokine (C-X-C motif) ligand 5|epithelial-derived neutrophil-activating protein 78|neutrophil-activating peptide ENA-78|neutrophil-activating protein 78|small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

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