Recombinant Human IL-16 (121 a.a.) Protein

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues.

Product Info Summary

SKU: PROTQ14005-3
Size: Various Sizes
Origin Species: Mouse
Source: E. Coli
Application: Cell Culture

Product Name

Recombinant Human IL-16 (121 a.a.) Protein

See all IL-16 products

SKU/Catalog Number

PROTQ14005-3

Size

Various Sizes

Form

Solid; white powder or thin/invisible film

Description

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.3 kDa protein consisting of 129 amino acid residues.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Recombinant Human IL-16 (121 a.a.) Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ14005-3)

Formulation

Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.

Predicted MW

141.752kDa

Biological Activity And Protein Authenticity

Determined by its ability ot chemoattract human CD4+ T-Lymphocytes using a concentration range of 50.0-100.0 ng/ml.

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Validation Images & Assay Conditions

Gene/Protein Information For IL16 (Source: Uniprot.Org, NCBI)

Uniprot ID

Q14005

Gene ID

3603

Gene Name

IL16

Full Name

Pro-interleukin-16

Weight

141.752kDa

Alternative Names

FLJ16806; FLJ42735; FLJ44234; HsT19289; IL16; IL-16; interleukin 16 (lymphocyte chemoattractant factor); LCF; LCFprIL-16; lymphocyte chemoattractant factor; neuronal interleukin 16; NIL16; PRIL16; prointerleukin 16; pro-interleukin-16 IL16 LCF, NIL16, PRIL16, prIL-16 interleukin 16 pro-interleukin-16|lymphocyte chemoattractant factor|neuronal interleukin 16|prointerleukin 16

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

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IL16 infographic

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Size

Total: $230

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