Recombinant Murine LIX (CXCL6) [93a.a] Protein

LIX is a CXC chemokine that signals through the CXCR2 receptor.  It is expressed in monocytes, platelets, endothelial cells, and mast cells.  LIX is a chemoattractant for neutrophils.  The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively.  LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.  Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.

Product Info Summary

SKU: PROTP50228-3
Size: Various Sizes
Origin Species: Mouse
Source: E. Coli
Application: Cell Culture

Product Name

Recombinant Murine LIX (CXCL6) [93a.a] Protein

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SKU/Catalog Number

PROTP50228-3

Size

Various Sizes

Form

Solid; white powder or thin/invisible film

Description

LIX is a CXC chemokine that signals through the CXCR2 receptor.  It is expressed in monocytes, platelets, endothelial cells, and mast cells.  LIX is a chemoattractant for neutrophils.  The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively.  LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.  Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Recombinant Murine LIX (CXCL6) [93a.a] Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP50228-3)

Formulation

Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.

Predicted MW

14.235kDa

Biological Activity And Protein Authenticity

Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.

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Validation Images & Assay Conditions

Gene/Protein Information For Cxcl5 (Source: Uniprot.Org, NCBI)

Uniprot ID

P50228

Gene ID

20311

Gene Name

Cxcl5

Full Name

C-X-C motif chemokine 5

Weight

14.235kDa

Superfamily

intercrine alpha (chemokine CxC) family

Alternative Names

LIX Cxcl5|AMCF, AMCF-II, Cxcl, Cxcl6, ENA-, ENA-78, GCP-, GCP-2, L, LIX, Scyb, Scyb5, Scyb6|chemokine (C-X-C motif) ligand 5|C-X-C motif chemokine 5|cytokine LIX|granulocyte chemotactic protein-2|small inducible cytokine B subfamily, member 5|small inducible cytokine subfamily B, member 15|small-inducible cytokine B5

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

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PROTP50228-3
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