FTSJ1 Antibodies

AND FTSJ1 ELISA kits, FTSJ1 Proteins

Many biological assays use antibodies to detect FTSJ1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FTSJ1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FTSJ1 antibodies...

We validate the specificity of these antibodies to FTSJ1 by testing them on tissues known to express FTSJ1 positively and negatively. Browse below to find the FTSJ1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FTSJ1 Infographic by Boster Bio

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FTSJ1 (NM_012280) Human Over-expression Lysate

FTSJ1 Human Over-expression Lysates NM_012280

Human

$628
Cat # LS024140
20 µg, 100 µg

FTSJ1 Overview

Facts about Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase.

FTSJ1 3D structure. Source: alphafold

Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (FTSJ1)

Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. .

Gene Information

Human
Gene Name:	FTSJ1
Uniprot:	Q9UET6
Entrez:	24140

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

CDLIV; cell division protein; EC 2.1.1.-; FtsJ homolog 1 (E. coli); JM23; mental retardation, X-linked 44; mental retardation, X-linked 9; MRX44; Protein ftsJ homolog 1; putative ribosomal RNA methyltransferase 1; rRNA (uridine-2'-O-)-methyltransferase; SPB1MRX9; TRM7

Molecular Weight

Mass (kDA):
36.079 kDA

Genomic Context


Human

Location:	Xp11.23
Sequence:	X; NC_000023.11 (48476021..48486364)

Tissue Specificity

Found in fetal brain, lung, liver and kidney. In the adult brain, expressed in amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus.

Subcellular Localizations

Cytoplasm.

Diseases

Sex Chromosome Aberrations
Microcephaly
Chromosomal Duplication
Williams Syndrome
Craniofacial Abnormalities
Cerebellar Ataxia
Severe Mental Retardation
Cognition Disorders
Language Delays
Mental Disorders

Autistic Disorder
Fragile X Syndrome
Chromosomal Translocation
Dwarfism

Pathways

Translation
Brain Development
Metaphase
Cognition
Regulation Of Translation

PTMs

Reduction

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FTSJ1

References

PMID: 15162322 by Freude K., et al. Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine- binding protein cause nonsyndromic X-linked mental retardation.