Boster Bio Life Science Blog

  1. 2024 SOT Annual Meeting

    Meet us in Salt Lake City from March 10-14 at the Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo! Over 5,000 toxicologists and professionals attend this event to share the latest science and technology advancements, make new connections, and engage in professional development.

    Stop by Booth #1802 to pick up technical resources and an adorable Dr. Booster figurine! Come and discover how our products, services, and resources can boost your research. We hope to see you there...

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    2024 SOT Annual Meeting
  2. Happy Holidays!

    Season’s greetings from the entire Boster team!

    May your holidays be full of love, joy, and hope. Wishing you peace, happiness, and success in the new year!

    Thank you for your support in 2023 and we look forward to continuing to serve you in the upcoming year.

    Have a Merry Christmas and a Happy New Year...

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    Happy Holidays!
  3. Research Spotlight - December 2023

    Welcome to the latest issue of Research Spotlight! We're excited to dive into biomedical breakthroughs that are impacting health and disease research.

    In the field of neuroscience, research revealed how stress affects the brain, particularly the red nucleus, and its link to anxiety and immune responses. This insight has implications for treating mental health disorders. In respiratory research, a new study advanced our understanding of how the lungs detect allergens, opening up possibilities...

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    Research Spotlight - December 2023
  4. Holiday Sale: 50% OFF on Antibodies and ELISA kits

    Stock up on primary antibodies and ELISA kits with our holiday sale! From now until the end of 2023, we're offering 50% OFF on all PicoKine® ELISA kits and Picoband™ antibodies!

    When placing your order, submit the promo code PICO50 at checkout, or through phone or email, to apply the 50% discount.

    The promotion ends on December 31, 2023. Take advantage of...

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    Holiday Sale: 50% OFF on Antibodies and ELISA kits
  5. Research Spotlight - November 2023

    Welcome to this month’s Research Spotlight! In this issue, we are excited to showcase our customers’ new studies that are shaping the future of biomedicine.

    In the field of neurology, researchers investigated a critical pathway, p300/NF-κB/NLRP3, impacted by disruptions in chaperone-mediated autophagy, which holds promise for treatments in neurodegenerative diseases. For regenerative medicine, scientists introduced a metal-organic framework-incorporated hydrogel that...

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    Research Spotlight - November 2023
  6. Will you be at Neuroscience 2023?

    Neuroscience 2023 is taking place in Washington, D.C. at Walter E. Washington Convention Center from November 11-15. Join 30,000 scientists from around the world to discover hot topics and tools for neuroscience!

    Meet us at Booth# 2104 to pick up some Boster goodies including pathway posters, technical resources, free phone accessories, and a Dr. Booster plush doll!

    Come and discover how our products, services, and resources can boost your research. We hope to see you there...

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    Will you be at Neuroscience 2023?
  7. Research Spotlight - October 2023

    As autumn leaves turn golden, Boster Bio is excited to present a medley of pioneering studies that have recently been published. This month’s issue covers a spectrum from novel therapeutic interventions to insightful multi-omics analyses.

    In the therapeutic domain, we spotlight a novel implantable hydrogel-based sensor that allows for real-time drug monitoring in rats. We also observe a shift in cancer treatments with a new cocktail nanovaccine. Additionally, fresh approaches are introduced for targeting lung fibrosis using mitochondrial transfer and enhancing liver cancer treatments with artesunate.

    On a molecular scale, studies revealed how indoor air pollutants impact liver health and blood lipid levels. Scientists also investigated the protective role of gut fungi against intestinal issues and the potential of mung bean sprout nanoparticles in diabetes management. Moreover, recent findings linked a compound in the colon, phosphocholine, with a specific fungus Candida tropicalis, highlighting mycobiota’s importance for our digestive health.

    Scroll down to learn more about these discoveries!

    Implantable Hydrogel-Protective DNA Aptamer-Based Sensor Supports Accurate, Continuous Electrochemical Analysis of Drugs at Multiple Sites in Living Rats

    Authors: Li, S., Dai, J., Zhu, M., Currás, N.A., Li, H., Wang, Y., Wang, Q…
    Journal: ACS Nano

    The ability to track the levels of specific molecules, such as drugs, metabolites, and biomarkers, in the living body, in real time and for long durations, would improve our understanding of health and our ability to diagnose, treat, and monitor disease. To this end, we are developing electrochemical aptamer-based (EAB) biosensors...

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    Cited Boster Product(s): Rat IL-12(P70) ELISA Kit PicoKine® (EK1652); Rat Endothelin 1/EDN1 ELISA Kit PicoKine® (EK0952)

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    Efficient Intervention for Pulmonary Fibrosis via Mitochondrial Transfer Promoted by Mitochondrial Biogenesis

    Authors: Huang, T., Lin, R., Su, Y., Sun, H., Zheng, X., Zhang, J., Lu, X…
    Journal: Nature Communications

    The use of exogenous mitochondria to replenish damaged mitochondria has been proposed as a strategy for the treatment of pulmonary fibrosis. However, the success of this strategy is partially restricted by the difficulty of supplying sufficient mitochondria to diseased cells. Herein, we report the generation of high-powered mesenchymal...

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    Cited Boster Product(s): Mouse MMP-9 ELISA Kit PicoKine® (EK0466); Mouse TGF Beta 1 ELISA Kit PicoKine® (EK0515); 4% Paraformaldehyde (PFA) Solution In PBS (AR1068); Anti-Ki67/MKI67 Antibody Picoband™ (PB9026); Goat Anti-Rabbit IgG (H+L) Secondary Antibody, FITC Conjugated (BA1105)

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    In Situ Cocktail Nanovaccine for Cancer Immunotherapy

    Authors: Liu, M., Xie, D., Hu, D., Zhang, R., Wang Y., Tang, L., Zhou, B…
    Journal: Advanced Science

    In situ vaccination is a desirable strategy for cancer immunotherapy due to its convenience and capacity to target tumor antigens. Here, an in situ nanovaccine based on a cationic peptide with cholesterol-modified, DP7-C, for cancer immunotherapy is rationally designed, and developed a cancer nanovaccine that is easy to preparate...

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    Cited Boster Product(s): Mouse TNF Alpha/Tumor Necrosis Factor ELISA Kit PicoKine® (EK0527)

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    Artesunate Sensitizes Human Hepatocellular Carcinoma to Sorafenib via Exacerbating AFAP1L2-SRC-FUNDC1 Axis-Dependent Mitophagy

    Authors: Ma, Z., Chen, W., Liu, Y., Yu, L., Mao, X., Guo, X., Jiang, F., Guo, Q…
    Journal: Autophagy

    Sorafenib is the most widely used first-line drug for the treatment of the advanced hepatocellular carcinoma (HCC). Unfortunately, sorafenib resistance often limits its therapeutic efficacy. To evaluate the efficacy of artesunate against sorafenib-resistant HCC and to investigate its underlying pharmacological mechanisms...

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    Cited Boster Product(s): Citrate Buffer Powder (AR0024)

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    Global Analysis of HLA-A2 Restricted MAGE-A3 Tumor Antigen Epitopes and Corresponding TCRs in Non-Small Cell Lung Cancer

    Authors: Zhang, B., Ren, Z., Zhao, J., Zhu, Y., Huang, B., Xiao, C., Zhang, Y…
    Journal : Theranostics

    Background: Advanced non-small cell lung cancer (NSCLC) is the most common type of lung cancer with poor prognosis. Adoptive cell therapy using engineered T-cell receptors (TCRs) targeting cancer-testis antigens, such as Melanoma-associated antigen 3 (MAGE-A3), is a potential approach for the treatment of NSCLC. However, systematic...

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    Cited Boster Product(s): HRP Conjugated AffiniPure Goat Anti-Rabbit IgG (H+L) (BA1054)

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    Multi-Omics Analysis Reveals Hepatic Lipid Metabolism Profiles and Serum Lipid Biomarkers Upon Indoor Relevant VOC Exposure

    Authors: Miao, G., Wang, Y., Wang, B., Yu, H., Liu, J., Pan, R., Zhou, C…
    Journal: Environment International

    As a widespread indoor air pollutant, volatile organic compound (VOC) caused various adverse health effects, especial the damage to liver, which has become a growing public concern. However, the current toxic data are intrinsically restricted in the single or major VOC species. Limited knowledge is available regarding toxic effects...

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    Research Spotlight - October 2023
  8. Natural Killer (NK) Cell Markers

    Representing 5-20% of the circulating group 1 innate lymphoid cells (ILCs), natural killer (NK) cells play a crucial role in the innate immune system. They were named ‘natural killer’ due to their ability to recognize and kill physiologically stressed cells (tumor cells or virus-infected cells) without the presence/activation of typical markers for immune system activation, such as antibodies or major histocompatibility complex (MHC) on cell surfaces (Abel et al., 2018; Guia et al., 2018; Pol...

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    Natural Killer (NK) Cell Markers
  9. Research Spotlight - September 2023

    This month, we're excited to spotlight a selection of cutting-edge research studies that have benefited from Boster Bio's high-quality products.

    Several studies this month deepen our understanding of disease mechanisms, including the role of pancreatic acinar cells in chronic pancreatitis fibrosis and the intriguing connections between the PCCB gene, associated with schizophrenia, and GABAergic pathways.

    On the therapeutic front, different innovative methods have emerged, from an injectable hydrogel for osteoarthritis therapy to the promising rapid antidepressant-like effects of the connexin hemichannel inhibitor D4. Immunotherapy has also taken a front seat, with new research on IL2Rbg targeting combined with radiotherapy in HNSCC, and the screening of potential vaccines against Mycoplasma synoviae.

    Scroll down to learn more and uncover insights from these new research studies!

    Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells

    Authors: Wang, D., Han, S., Lv, G., Hu, Y., Zhuo, W., Zeng, Z., Tang, J…
    Journal: Gastroenterology

    BACKGROUND AND AIMS: Studies have demonstrated that the activated pancreatic stellate cells (PSCs) play a crucial role in pancreatic fibrogenesis in chronic pancreatitis (CP), while the precise mechanism for PSCs activation has not been fully elucidated. We analyzed that the role of injured pancreatic acinar cells (iPACs)...

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    Cited Boster Product(s): Goat Anti-Rabbit IgG (H+L) Secondary Antibody, Cy3 Conjugated (BA1032)

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    Selective Targeting of IL2Rbg Combined With Radiotherapy Triggers CD8- and NK-Mediated Immunity, Abrogating Metastasis in HNSCC

    Authors: Gadwa, J., Amann, M., Bickett, T.E., Knitz, M.W., Darragh, L.B…
    Journal: Cell Reports Medicine

    The implementation of cancer immunotherapies has seen limited clinical success in head and neck squamous cell carcinoma (HNSCC). Interleukin-2 (IL-2), which modulates the survival and functionality of lymphocytes, is an attractive target for new immunotherapies but one that is limited by presence of regulatory T cells (Tregs)...

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    Cited Boster Product(s): Human IL-2/Interleukin-2 ELISA Kit PicoKine® (EK0397)

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    Human Forebrain Organoid-Based Multi-Omics Analyses of PCCB as a Schizophrenia Associated Gene Linked to GABAergic Pathways

    Authors: Zhang, W., Zhang, M., Xu, Z., Yan, H., Wang, H., Jiang, J., Wan, J…
    Journal: Nature Communications

    Identifying genes whose expression is associated with schizophrenia (SCZ) risk by transcriptome-wide association studies (TWAS) facilitates downstream experimental studies. Here, we integrated multiple published datasets of TWAS, gene coexpression, and differential gene expression analysis to prioritize SCZ candidate genes for functional...

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    Cited Boster Product(s): Goat Anti-Mouse IgG (H+L) Secondary Antibody, Cy3 Conjugated (BA1031)

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    Injectable Photocrosslinking Spherical Hydrogel-Encapsulated Targeting Peptide-Modified Engineered Exosomes for Osteoarthritis Therapy

    Authors: Wan, J., He, Z., Peng, R., Wu, X., Zhu, Z., Cui, J., Hao, X., Chen, A…
    Journal: Journal of Nanobiotechnology

    Osteoarthritis (OA) is a common degenerative joint disease urgently needing effective treatments. Bone marrow mesenchymal stromal cell-derived exosomes (Exo) are considered good drug carriers whereas they have limitations such as fast clearance and low retention. This study aimed to overcome the limitations of Exo in drug delivery...

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    Cited Boster Product(s): Anti-SOX9 Antibody Picoband™ (A00177-2); Goat

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    Research Spotlight - September 2023
  10. Our new warehouse in Europe

    Good news! We're happy to announce that we have established a warehouse in the Netherlands that has already started operations! With our new warehouse, we hope to enable faster shipping for all our customers in Europe. For products in stock, this arrangement will significantly reduce lead time.

    To check if a product is in stock at our Netherlands warehouse, please visit any product page and select “Europe (including UK)” in the “Add to Cart”/“Get a Quote” box, which will display sto...

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    Our new warehouse in Europe