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- Table of Contents
Facts about Immunoglobulin heavy variable 3-48.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).
Human | |
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Gene Name: | IGHV3-48 |
Uniprot: | P01763 |
Entrez: | 28424 |
Belongs to: |
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No superfamily |
Immunoglobulin heavy variable 3-48
Mass (kDA):
12.813 kDA
Human | |
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Location: | 14q32.33 |
Sequence: | 14; NC_000014.9 (106537810..106538265, complement) |
Secreted. Cell membrane.
PMID: 6410398 by Goni F., et al. Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.