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- Table of Contents
Facts about Immunoglobulin heavy variable 4-39.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).
Human | |
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Gene Name: | IGHV4-39 |
Uniprot: | P01824 |
Entrez: | 28394 |
Belongs to: |
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No superfamily |
Immunoglobulin heavy variable 4-39
Mass (kDA):
13.917 kDA
Human | |
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Location: | 14q32.33 |
Sequence: | 14; NC_000014.9 (106421709..106422147, complement) |
Secreted. Cell membrane.
PMID: 6806818 by Takahashi N., et al. Complete amino acid sequence of the delta heavy chain of human immunoglobulin D.
PMID: 16157351 by Sun Z., et al. Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering.