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- Table of Contents
Facts about Immunoglobulin kappa variable 2D-28.
In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).
Human | |
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Gene Name: | IGKV2D-28 |
Uniprot: | P01615 |
Entrez: | 28883 |
Belongs to: |
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No superfamily |
Immunoglobulin kappa variable 2D-28
Mass (kDA):
12.957 kDA
Human | |
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Location: | 2p11.2 |
Sequence: | 2; NC_000002.12 (89960015..89960747) |
Secreted. Cell membrane.
PMID: 6325927 by Klobeck H.G., et al. Contribution of human V kappa II germ-line genes to light-chain diversity.
PMID: 4596149 by Putnam F.W., et al. Amino acid sequence of a kappa Bence Jones protein from a case of primary amyloidosis.