IGKV3-20 Antibodies

AND IGKV3-20 ELISA kits, IGKV3-20 Proteins

Many biological assays use antibodies to detect IGKV3-20, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGKV3-20 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGKV3-20 antibodies...

We validate the specificity of these antibodies to IGKV3-20 by testing them on tissues known to express IGKV3-20 positively and negatively. Browse below to find the IGKV3-20 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGKV3-20 Infographic by Boster Bio

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IGKV3-20 Overview

Facts about Immunoglobulin kappa variable 3-20.

IGKV3-20 3D structure. Source: alphafold

Immunoglobulin kappa variable 3-20 (IGKV3-20)

V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.

In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).

Gene Information

Human
Gene Name:	IGKV3-20
Uniprot:	P01619
Entrez:	28912

Family

Belongs to:

No superfamily

Alternative Names

Immunoglobulin kappa variable 3-20

Molecular Weight

Mass (kDA):
12.557 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (89142574..89143108, complement)

Subcellular Localizations

Secreted. Cell membrane.

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGKV3-20

References

PMID: 2997711 by Klobeck H.G., et al. Human immunoglobulin kappa light chain genes of subgroups II and III.

PMID: 3127527 by Kipps T.J., et al. Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.