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- Table of Contents
ADAM19 Antibodies
AND ADAM19 ELISA kits, ADAM19 Proteins
Many biological assays use antibodies to detect ADAM19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM19 antibodies...
Designing a Western blot for ADAM19? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ADAM19 Western Blot GuideADAM19 Infographic by Boster Bio
All ADAM19 Products
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ADAM19 Overview
Facts about Disintegrin and metalloproteinase domain-containing protein 19.
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19)
Participates in the proteolytic processing of beta-type neuregulin isoforms that are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin.
May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | ADAM19 |
| Uniprot: | Q9H013 |
| Entrez: | 8728 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
a disintegrin and metalloproteinase domain 19 (meltrin beta); ADAM 19; ADAM metallopeptidase domain 19; ADAM19; disintegrin and metalloproteinase domain-containing protein 19; EC 3.4.24; EC 3.4.24.-; MADDAM; Meltrin beta; meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker; MLTNBmeltrin beta
Molecular Weight
Mass (kDA):
104.997 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q33.3 |
| Sequence: | 5; NC_000005.10 (157477304..157575775, complement) |
Tissue Specificity
Expressed in many normal organ tissues and several cancer cell lines.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Cell Invasion
- Neoplasms
- Congenital Abnormality
- Adenocarcinoma
- Crest Syndrome
- Lung Diseases
- Fibrosis
- Heart Diseases
- Nervousness
- Congenital Heart Defects
- Congenital Heart Disease
Pathways
- Cell Migration
- Localization
- Cell Adhesion
- Neurogenesis
- Pathogenesis
- Heart Development
- Proteolysis
- Secretion
- Cell Differentiation
- Zymogen Activation
- Myelination
- Embryo Implantation
- Myoblast Fusion
PTMs
- Cleavage
- Phosphorylation
Research Areas
- Dendritic Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM19
bosterbio.com/bosterbio-gene-info-cards/ADAM19
References
PMID: 10887142 by Fritsche J., et al. Molecular cloning and characterization of a human metalloprotease disintegrin a novel marker for dendritic cell differentiation.
PMID: 11162584 by Wei P., et al. Expression and enzymatic activity of human disintegrin and metalloproteinase ADAM19/meltrin beta.