ADAM19 Antibodies

AND ADAM19 ELISA kits, ADAM19 Proteins

Many biological assays use antibodies to detect ADAM19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM19 antibodies...

We validate the specificity of these antibodies to ADAM19 by testing them on tissues known to express ADAM19 positively and negatively. Browse below to find the ADAM19 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADAM19 Infographic by Boster Bio

All ADAM19 Products

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Specificity

Applications

Price

Anti-ADAM19 Antibody Picoband®

1 Citations 5 Q&As

Western blot analysis of ADAM19 using anti-ADAM19 antibody (PA2070)

Human

$370
Cat # PA2070
100 μg/vial

ADAM19 (NM_033274) Human Over-expression Lysate

Human

$960
Cat # LS008728
20 µg, 100 µg

ADAM19 Overview

Facts about Disintegrin and metalloproteinase domain-containing protein 19.

ADAM19 3D structure. Source: alphafold

Disintegrin and metalloproteinase domain-containing protein 19 (ADAM19)

Participates in the proteolytic processing of beta-type neuregulin isoforms that are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin.

May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). .

Gene Information

Human
Gene Name:	ADAM19
Uniprot:	Q9H013
Entrez:	8728

Family

Belongs to:

No superfamily

Alternative Names

a disintegrin and metalloproteinase domain 19 (meltrin beta); ADAM 19; ADAM metallopeptidase domain 19; ADAM19; disintegrin and metalloproteinase domain-containing protein 19; EC 3.4.24; EC 3.4.24.-; MADDAM; Meltrin beta; meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker; MLTNBmeltrin beta

Molecular Weight

Mass (kDA):
104.997 kDA

Genomic Context


Human

Location:	5q33.3
Sequence:	5; NC_000005.10 (157477304..157575775, complement)

Tissue Specificity

Expressed in many normal organ tissues and several cancer cell lines.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Malignant Neoplasms
Cell Invasion
Neoplasms
Congenital Abnormality
Adenocarcinoma
Crest Syndrome
Lung Diseases
Fibrosis
Heart Diseases
Nervousness
Congenital Heart Defects
Congenital Heart Disease

Alzheimer's Disease
Ventricular Septal Defects
Ovarian Neoplasm
Malignant Paraganglionic Neoplasm
Atrophy
Chronic Obstructive Airway Disease
Malignant Neoplasm Of Ovary

Pathways

Cell Migration
Localization
Cell Adhesion
Neurogenesis
Pathogenesis
Heart Development
Proteolysis
Secretion
Cell Differentiation
Zymogen Activation
Myelination
Embryo Implantation
Myoblast Fusion

Secretory Pathway
Cell Proliferation
Neural Crest Cell Migration
Fertilization
Cell Growth
Rna Interference
Cell Activation

PTMs

Cleavage
Phosphorylation

Methylation
Deacetylation

Acetylation

Research Areas

Dendritic Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM19

References

PMID: 10887142 by Fritsche J., et al. Molecular cloning and characterization of a human metalloprotease disintegrin a novel marker for dendritic cell differentiation.

PMID: 11162584 by Wei P., et al. Expression and enzymatic activity of human disintegrin and metalloproteinase ADAM19/meltrin beta.