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- Table of Contents
1 Citations 3 Q&As
Facts about Arf-GAP domain and FG repeat-containing protein 1.
In the event of disease by HIV-1, functions as a cofactor for viral Rev and promotes motion of Rev-responsive element- containing RNAs in the nuclear periphery to the cytoplasm. This step is vital for HIV-1 replication.
| Human | |
|---|---|
| Gene Name: | AGFG1 |
| Uniprot: | P52594 |
| Entrez: | 3267 |

| Belongs to: |
|---|
| No superfamily |

ArfGAP with FG repeats 1; DKFZp686I15205; HIV-1 Rev-binding protein; HRBRev interacting protein; Rab, Rev/Rex activation domain-binding protein; RABMGC116938; RIPMGC116940
Mass (kDA):
58.26 kDA

| Human | |
|---|---|
| Location: | 2q36.3 |
| Sequence: | 2; NC_000002.12 (227472169..227561222) |
Ubiquitously expressed.
Nucleus. Cytoplasmic vesicle.





PMID: 7634337 by Bogerd H.P., et al. Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.
PMID: 7637788 by Fritz C.C., et al. A human nucleoporin-like protein that specifically interacts with HIV Rev.