AGFG1 Antibodies

AND AGFG1 ELISA kits, AGFG1 Proteins

Many biological assays use antibodies to detect AGFG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGFG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGFG1 antibodies...

We validate the specificity of these antibodies to AGFG1 by testing them on tissues known to express AGFG1 positively and negatively. Browse below to find the AGFG1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for AGFG1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the AGFG1 Western Blot Guide

AGFG1 Infographic by Boster Bio

All AGFG1 Products

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Specificity

Applications

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Anti-AGFG1 Antibody Picoband®

1 Citations

IF analysis of AGFG1 using anti-AGFG1 antibody (RP1071)

Flow Cytometry analysis of SiHa cells using anti-AGFG1 antibody (RP1071)

Western blot analysis of AGFG1 using anti-AGFG1 antibody (RP1071)

Human, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # RP1071
100 μg/vial

AGFG1 (NM_004504) Human Over-expression Lysate

AGFG1 Human Over-expression Lysates NM_001135187

Human

$628
Cat # LS003267
20 µg, 100 µg

Anti-AGFG1 Antibody

Western blot analysis of extracts of various cell lines, using AGFG1 antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A03560
100ul

AGFG1 Overview

Facts about Arf-GAP domain and FG repeat-containing protein 1.

AGFG1 3D structure. Source: alphafold

Arf-GAP domain and FG repeat-containing protein 1 (AGFG1)

Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization.

In the event of disease by HIV-1, functions as a cofactor for viral Rev and promotes motion of Rev-responsive element- containing RNAs in the nuclear periphery to the cytoplasm. This step is vital for HIV-1 replication.

Gene Information

Human
Gene Name:	AGFG1
Uniprot:	P52594
Entrez:	3267

Family

Belongs to:

No superfamily

Alternative Names

ArfGAP with FG repeats 1; DKFZp686I15205; HIV-1 Rev-binding protein; HRBRev interacting protein; Rab, Rev/Rex activation domain-binding protein; RABMGC116938; RIPMGC116940

Molecular Weight

Mass (kDA):
58.26 kDA

Genomic Context


Human

Location:	2q36.3
Sequence:	2; NC_000002.12 (227472169..227561222)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Cytoplasmic vesicle.

Diseases

Malignant Neoplasms
Neoplasms
Hiv Infections
Immunologic Deficiency Syndromes
Inflammation
Cell Transformation, Neoplastic
Virus Diseases
Leukemia
Carcinoma
Cytomegalovirus Infections
Malignant Paraganglionic Neoplasm
Genotoxic Stress

Carcinogenesis
Glioblastoma
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Mammary Neoplasms
L1 Acute Lymphoblastic Leukemia
Ovarian Neoplasm

Interacting Proteins

NYAP2
POLE2
VAMP7

Pathways

Cell Death
Nuclear Export
Transport
Necroptosis
Necrotic Cell Death
Localization
Sensitization
Nucleocytoplasmic Transport
Rna Interference
Autophagy
Translation
Cell Activation
Nuclear Transport

Cell Differentiation
Programmed Cell Death
Immune Response
Proteolysis
Ripoptosome Assembly
Endocytosis
Conjugation

PTMs

Ubiquitination
Phosphorylation
Cleavage

Sumoylation
Nitration
Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGFG1

References

PMID: 7634337 by Bogerd H.P., et al. Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.

PMID: 7637788 by Fritz C.C., et al. A human nucleoporin-like protein that specifically interacts with HIV Rev.