Arf-GAP domain and FG repeat-containing protein 1 (AGFG1)

Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization.

In the event of disease by HIV-1, functions as a cofactor for viral Rev and promotes motion of Rev-responsive element- containing RNAs in the nuclear periphery to the cytoplasm. This step is vital for HIV-1 replication.