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- Table of Contents
Facts about Homeobox protein ARX.
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Mouse | |
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Gene Name: | Arx |
Uniprot: | O35085 |
Entrez: | 11878 |
Belongs to: |
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paired homeobox family |
aristaless related homeobox; Aristaless-related homeobox; aristaless-related homeobox, X-linked; ARX; cancer/testis antigen 121; CT121; EIEE1; homeobox protein ARX; ISSX; ISSXmental retardation, X-linked 36; mental retardation, X-linked 29; mental retardation, X-linked 32; mental retardation, X-linked 33; mental retardation, X-linked 38; mental retardation, X-linked 43; mental retardation, X-linked 54; mental retardation, X-linked 76; mental retardation, X-linked 87; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS
Mass (kDA):
58.49 kDA
Mouse | |
---|---|
Location: | X C3|X 41.05 cM |
Sequence: | X; |
Boster Bio is a molecular biologist that specializes in ELISA testing. This company was founded in 1993, and is well-known for its signature ELISA products. However, they have recently expanded their offerings to include PCR-related molecular biology products as well. Boster Bio offers many services for scientists, including 24 hour customer support and technical resources.
The Food and Drug Administration has approved ARX Marker as a new fluorescent dye. Boster created his first product back in 1993. He's been called "the scientist from the lavatory". His company has grown into one of China's largest catalog antibody companies. He has also developed his own proprietary ELISA platform called PicoKine(tm). It uses proprietary trade secrets in order to produce high-sensitivity ELISA tests.
The ARX gene plays a major role in nearly all fundamental processes in the human brain. It plays an important role in neuronal cell proliferation and differentiation, cell maturation as well as cell maturation. This review summarizes the latest findings on the role of ARX genes in brain development and the pathophysiology associated with mental retardation or epilepsy due to ARX mutations. In addition, we discuss the role of the ARX gene in the regulation of neuronal growth and development.
The ARX gene is essential for male reproduction in a rostral migration stream. This pathway allows newly-generated neurons to migrate towards the olfactory bulbs. The gene is present in all mammals, and is thought to play an important role in cellular morphology and process formation. Although the role of ARX in the development or reproduction of reproductive capacity is still not fully understood, scientists know that it is involved with regulating reproduction.
The ARX family of proteins includes a number of proteins called paired homeobox. It is expressed in the embryonic and adult telencephalons, cortical GABAergic nerves, and neuronal stem cell. It promotes alpha and Beta cell differentiation. Its structure is characterized by an octapeptide motif that binds Groucho proteins. It shares 97% with the human ARX genes, which is its amino acid sequence.
Boster Bio Molecular marks' COL4AA2 markers detect canstatin within a variety ocell types. This product is suitable in vitro and has high affinity. Its anti-angiogenic properties also make it suitable for cancer immunotherapy clinical trials. It can be used to identify tumor growth and COL4A1/A2 decay. These markers are useful in many applications, including cell culture and biomedical research.
Boster Bio's genomic infographics are a great resource if you are looking for an easy-to read resource to help you navigate the worlds of genetics. They feature gene informationgraphics for both the human and mouse genomes and can be searched by gene or species name. This makes it easy to pinpoint a particular gene of interest to you. Here are some of the highlights from Boster’s Genome Infographics.
PMID: 9256348 by Miura H., et al. Expression of a novel aristaless related homeobox gene 'Arx' in the vertebrate telencephalon, diencephalon and floor plate.