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Axin-2 Antibodies

AND AXIN2 ELISA kits, Axin-2 Proteins

Many biological assays use antibodies to detect Axin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Axin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Axin-2 antibodies...

We validate the specificity of these antibodies to Axin-2 by testing them on tissues known to express AXIN2 positively and negatively. Browse below to find the AXIN2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AXIN2 Infographic by Boster Bio

AXIN2 protein infographic

All AXIN2 Products

Product

Figures

Specificity

Applications

Price

Anti-Axin2/Conductin Rabbit Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M01772
100 μl

Anti-Axin-2 AXIN2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A01772
0.1 mg

Anti-Axin-2 Axin2 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01772-1
100ul

Anti-Axin 2/AXIN2 Antibody Picoband™

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A01772-2
100 μg/vial

Axin 2 (AXIN2) (NM_004655) Human Over-expression Lysate

Human

$628
Cat # LS008313
100 µg

AXIN2 Overview

Facts about Axin-2.

AXIN2 3D structure

AXIN2 3D structure. Source: alphafold

Axin-2 (AXIN2)

Inhibitor of the Wnt signaling pathway.
Down-regulates beta-catenin.

Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity). .

Gene Information

Human
Gene Name:	AXIN2
Uniprot:	Q9Y2T1
Entrez:	8313

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

AXIL; axin 2; Axin2; Axin-2; Axin-like protein; Axis inhibition protein 2; Conductin; DKFZp781B0869; MGC10366; MGC126582

Molecular Weight

Mass (kDA):
93.558 kDA

Molecular Weight

Genomic Context


Human

Location:	17q24.1
Sequence:	17; NC_000017.11 (65528563..65561648, complement)

Tissue Specificity

Expressed in brain and lymphoblast.

Subcellular Localizations

Cytoplasm.

Subcellular Localization

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Colorectal Cancer
Cell Transformation, Neoplastic
Polyposis
Colorectal Neoplasms
Adenomatous Polyposis Coli
Congenital Absence
Carcinogenesis
Hypodontia
Malignant Tumor Of Colon
Colonic Neoplasms

Developmental Absence Of Tooth
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Adenoma
Liver Neoplasms
Congenital Abnormality

Disease

Interacting Proteins

AMER3
CTNNB1
PLK1
PPP2CB
TGIF1

Interacting Proteins

Pathways

Cell Proliferation
Localization
Segmentation
Cell Growth
Pathogenesis
Mismatch Repair
Regeneration
Cell Cycle
Somitogenesis
Methylation
Cell Differentiation
Odontogenesis
Rna Interference

Cell Death
Cell Adhesion
Ossification
Osteoblast Differentiation
Tissue Homeostasis
Osteoblast Proliferation
Dentinogenesis

Pathways

PTMs

Phosphorylation
Methylation
Ubiquitination
Sumoylation
Biotinylation

Reduction
Deacetylation
Glycosylation
Cleavage
Dephosphorylation

Research Areas

Signal Transduction
Wnt Signaling Pathway

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AXIN2

References

PMID: 10049590 by Mai M., et al. Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24.

PMID: 11017067 by Liu W., et al. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.