Bach2 Antibodies

AND Bach2 ELISA kits, Bach2 Proteins

Many biological assays use antibodies to detect Bach2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bach2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bach2 antibodies...

We validate the specificity of these antibodies to Bach2 by testing them on tissues known to express Bach2 positively and negatively. Browse below to find the Bach2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Bach2 Infographic by Boster Bio

All Bach2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Bach2 Antibody

1 Q&As

Mouse

ELISA, IP, WB

$641
Cat # A04096
100ug

BACH2 (NM_021813) Human Over-expression Lysate

Human

$960
Cat # LS060468
20 µg, 100 µg

Bach2 Overview

Facts about Transcription regulator protein BACH2.

Transcription regulator protein BACH2 (Bach2)

Transcriptional regulator that acts as repressor or activator (PubMed:8887638). Binds to Maf recognition elements (MARE) (PubMed:8887638).

Plays an essential role in coordinating transcription activation and repression by MAFK (PubMed:8887638). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (By similarity).

Gene Information

Mouse
Gene Name:	Bach2
Uniprot:	P97303
Entrez:	12014

Family

Belongs to:

bZIP family

Alternative Names

BTB and CNC homolog 2; BTB and CNC homology 1, basic leucine zipper transcription factor 2; transcription regulator protein BACH2

Molecular Weight

Mass (kDA):
91.836 kDA

Genomic Context


Mouse

Location:	4\|4 A5
Sequence:	4;

Tissue Specificity

Detected in brain and spleen.

Diseases

Lymphoma
Leukemia
Neoplasms
Malignant Neoplasms
B-cell Lymphomas
Myeloid Leukemia
Leukemogenesis
Myeloid Leukemia, Chronic
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Diffuse Large B-cell Lymphoma
Lymphoma, Non-hodgkin
Burkitt Lymphoma

Carcinoma
Diabetes Mellitus, Insulin-dependent
Multiple Myeloma
Lymphoma, Follicular
Chromosomal Translocation
Crohn Disease
Cytogenetic Abnormality

Pathways

Cell Differentiation
Plasma Cell Differentiation
Nuclear Export
Cell Proliferation
Localization
Immune Response
Cell Death
Cell Cycle
Cell Growth
Germinal Center Formation
Response To Oxidative Stress
Humoral Immune Response
B Cell Differentiation

Pathogenesis
Cell Adhesion
Cell Activation
Mature B Cell Differentiation
Cell Fate Commitment
Dna Recombination
B Cell Activation

PTMs

Sumoylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Bach2

References

PMID: 8887638 by Oyake T., et al. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.

PMID: 10809773 by Hoshino H., et al. Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element.