BPI Antibodies

AND BPI ELISA kits, BPI Proteins

Many biological assays use antibodies to detect BPI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BPI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BPI antibodies...

We validate the specificity of these antibodies to BPI by testing them on tissues known to express BPI positively and negatively. Browse below to find the BPI antibody that suites your experiment. We have 16 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for BPI? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the BPI Western Blot Guide

BPI Infographic by Boster Bio

All BPI Products

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Product

Figures

Specificity

Applications

Price

Anti-BPIFB1 Antibody Picoband®

Western blot analysis of BPIFB1 using anti-BPIFB1 antibody (A08872-1)

Flow Cytometry analysis of HepG2 cells using anti-BPIFB1 antibody (A08872-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A08872-1
100 µg/vial

Anti-BPI Rabbit Monoclonal Antibody

Western blot analysis of BPI expression in THP1 lysate

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M01444
100 μl

Anti-LATH BPIFA4P Antibody

Immunofluorescence analysis of HeLa cells, using LATH Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using LATH Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$335
Cat # A30519
100ul

Plunc (BPIFA1) (NM_016583) Human Over-expression Lysate

Plunc (BPIFA1) Human Over-expression Lysates NM_016583

Human

$628
Cat # LS051297
20 µg, 100 µg

BPI (NM_001725) Human Over-expression Lysate

Human

$628
Cat # LS000671
20 µg, 100 µg

Anti-LATH BPIFA4P Antibody

Western blot (WB) analysis of LATH polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A16031-1
100ul

LPLUNC3 (BPIFB3) (NM_182658) Human Over-expression Lysate

Human

$960
Cat # LS359710
20 µg, 100 µg

BPIFC (NM_174932) Human Over-expression Lysate

Human

$960
Cat # LS254240
20 µg, 100 µg

SPLUNC3 (BPIFA3) (NM_001042439) Human Over-expression Lysate

Human

$628
Cat # LS128861
20 µg, 100 µg

BPIL1 (BPIFB2) (NM_025227) Human Over-expression Lysate

Human

$628
Cat # LS080341
20 µg, 100 µg

Anti-Plunc/BPIFA1 Antibody Picoband®

Western blot analysis of Plunc/BPIFA1 using anti-Plunc/BPIFA1 antibody (A03162-2)

Human, Mouse

ELISA, WB

$370
Cat # A03162-2
100 μg/vial

C20orf114 (BPIFB1) (NM_033197) Human Over-expression Lysate

Human

$628
Cat # LS092747
20 µg, 100 µg

C20orf186 (BPIFB4) (NM_182519) Human Over-expression Lysate

Human

$628
Cat # LS149954
100 µg

Plunc (BPIFA1) (NM_016583) Human Recombinant Protein

Coomassie blue staining of purified BPIFA1 protein

$1062
Cat # PROTQ9NP55
20 µg

SPLUNC3 (BPIFA3) (NM_001042439) Human Recombinant Protein

Coomassie blue staining of purified BPIFA3 protein

$1249
Cat # PROTQ9BQP9
20 µg

C20orf114 (BPIFB1) (NM_033197) Human Recombinant Protein

Coomassie blue staining of purified BPIFB1 protein

$1249
Cat # PROTQ8TDL5
20 µg

BPI Overview

Facts about Bactericidal permeability-increasing protein.

BPI 3D structure. Source: alphafold

Bactericidal permeability-increasing protein (BPI)

The cytotoxic activity of BPI is limited to a lot of species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very fundamental N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.

aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Gene Information

Human
Gene Name:	BPI
Uniprot:	P17213
Entrez:	671

Family

Belongs to:

BPI/LBP/Plunc superfamily

Alternative Names

bactericidal permeability-increasing protein; bactericidal/permeability-increasing protein; BPI; BPIFD1; CAP 57; rBPI

Molecular Weight

Mass (kDA):
53.9 kDA

Genomic Context


Human

Location:	20q11.23
Sequence:	20; NC_000020.11 (38304156..38337505)

Tissue Specificity

Restricted to cells of the myeloid series.

Subcellular Localizations

Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.

Diseases

Pain
Malignant Neoplasms
Depressive Disorder
Bipolar Disorder
Neoplasms
Infective Disorder
Systemic Infection
Inflammation
Anxiety Disorders
Chronic Pain
Bacterial Infections
Neoplasm Metastasis

Vasculitis
Mood Disorders
Gram-negative Bacterial Infections
Neuralgia
Fibrosis
Major Depressive Disorder
Cystic Fibrosis

Pathways

Pathogenesis
Immune Response
Secretion
Inflammatory Response
Phagocytosis
Localization
Transport
Cytokine Production
Innate Immune Response
Translation
Neutrophil Activation
Cell Activation
Opsonization

Cell Proliferation
Proteolysis
Virulence
Wound Healing
Aging
Respiratory Burst
Coagulation

PTMs

Cleavage
Phosphorylation
Glycosylation
Formylation
Biotinylation

Reduction
Carbamylation
Oxidation
Myristoylation
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BPI

References

PMID: 2722846 by Gray P.W., et al. Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations.

PMID: 7517398 by Wilde C.G., et al. Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS- mediated cell activation.