Cavin4 Antibodies

AND Cavin4 ELISA kits, Cavin4 Proteins

Many biological assays use antibodies to detect Cavin4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cavin4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cavin4 antibodies...

We validate the specificity of these antibodies to Cavin4 by testing them on tissues known to express Cavin4 positively and negatively. Browse below to find the Cavin4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cavin4 Infographic by Boster Bio

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CAVIN4 (NM_001018116) Human Over-expression Lysate

Human

$628
Cat # LS347273
20 µg, 100 µg

Cavin4 Overview

Facts about Caveolae-associated protein 4.

Caveolae-associated protein 4 (Cavin4)

Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and modulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes via MAPK1/3 activation (PubMed:24567387).

Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (PubMed:26497963). Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed:18332105).

Gene Information

Mouse
Gene Name:	Cavin4
Uniprot:	A2AMM0
Entrez:	68016

Family

Belongs to:

CAVIN family

Alternative Names

Caveolae-associated protein 4

Molecular Weight

Mass (kDA):
41.008 kDA

Genomic Context


Mouse

Location:	4\|4 B1
Sequence:	4;

Tissue Specificity

Abundantly expressed in cardiac and skeletal muscle (at protein level). Weaker expression in aorta and lung. In heart, expressed in cardiomyocytes and vascular smooth muscle cells but not in other surrounding cells including vascular endothelial cells.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cavin4

References

PMID: 18332105 by Ogata T., et al. MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance.

PMID: 19546242 by Bastiani M., et al. MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes.