CLCA4 Antibodies

AND CLCA4 ELISA kits, CLCA4 Proteins

Many biological assays use antibodies to detect CLCA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLCA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLCA4 antibodies...

We validate the specificity of these antibodies to CLCA4 by testing them on tissues known to express CLCA4 positively and negatively. Browse below to find the CLCA4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLCA4 Infographic by Boster Bio

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CLCA4 (NM_012128) Human Over-expression Lysate

Human

$628
Cat # LS022802
20 µg, 100 µg

CLCA4 Overview

Facts about Calcium-activated chloride channel regulator 4.

CLCA4 3D structure. Source: alphafold

Calcium-activated chloride channel regulator 4 (CLCA4)

May be involved in mediating calcium-activated chloride conductance. .

Gene Information

Human
Gene Name:	CLCA4
Uniprot:	Q14CN2
Entrez:	22802

Family

Belongs to:

CLCR family

Alternative Names

Calcium-activated chloride channel regulator 4

Molecular Weight

Mass (kDA):
101.283 kDA

Genomic Context


Human

Location:	1p22.3
Sequence:	1; NC_000001.11 (86547078..86580758)

Tissue Specificity

Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.

PTMs

Autocatalytic cleavage

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLCA4

References

PMID: 10437792 by Agnel M., et al. Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.

PMID: 15490240 by Ritzka M., et al. The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.