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We validate the specificity of these antibodies to CLPP by testing them on tissues known to express CLPP positively and negatively. Browse below to find the CLPP antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Facts about ATP-dependent Clp protease proteolytic subunit, mitochondrial.
The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and could be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. .
|peptidase S14 family|
ATP-dependent protease ClpAP, proteolytic subunit, human; ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli)homolog; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E.coli); ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog (E.coli); ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog; EC 220.127.116.11; Endopeptidase Clp; putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
|Sequence:||19; NC_000019.10 (6361531..6370242)|
Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.
In this article, we'll cover the advantages, applications, and optimization of the CLPP marker. You'll also find out about some troubleshooting tips and tricks. Boster Bio's optimization guides will help you make informed decisions and get better results. Every researcher has some difficulty in their experiments. Although there are many potential sources of error, proper controls will help eliminate many of these.
ACLPP, or the calmodulin-like protein, is a highly specific marker for many cell types. Its expression is normal in human oral muscosal cells. Its downregulation may be a sign of malignancy. This new marker may help to detect oral cancers in the early stages. In the meantime, it has several advantages for the clinical setting. Here are some of them.
CLPP is a member of the peptidase family S14. It cleaves various proteins by hydrolyzing ATP and may also play a role in maintaining general housekeeping functions. The CLPP marker was purified from human cells using conventional chromatography techniques. The recombinant human CLPP protein was expressed in E. coli and purified using conventional chromatography techniques. The CLPP marker is intended for research use only. The peptides and proteins are guaranteed for three months from receipt.
There are many advantages of using the CLPP marker. It is useful in many types of research. For example, it is used for gene expression analysis. And because of its broad range of uses, it can also be used in a variety of other applications. If you are interested in its potential as a diagnostic tool, you can check whether it is present in your sample. Boster Bio has a wide range of reagents and antibodies for this use.