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- Table of Contents
CLPP Antibodies
AND CLPP ELISA kits, CLPP Proteins
Many biological assays use antibodies to detect CLPP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLPP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLPP antibodies...
Designing a Western blot for CLPP? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CLPP Western Blot GuideCLPP Infographic by Boster Bio
All CLPP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01117-1
100 μg/vial
Cat # A01117-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01117-3
100 μg/vial
Cat # A01117-3
100 μg/vial
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M01117
100 µl
Cat # M01117
100 µl
CLPP Overview
Facts about ATP-dependent Clp protease proteolytic subunit, mitochondrial.
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP)
Protease part of the Clp complex that cleaves peptides and various proteins within an ATP-dependent process. Has low peptidase activity in the absence of CLPX.
The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and could be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CLPP |
| Uniprot: | Q16740 |
| Entrez: | 8192 |
Family
| Belongs to: |
|---|
| peptidase S14 family |
Alternative Names
ATP-dependent protease ClpAP, proteolytic subunit, human; ClpP (caseinolytic protease, ATP-dependent, proteolytic subunit, E. coli)homolog; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E.coli); ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog (E.coli); ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog; EC 3.4.21.92; Endopeptidase Clp; putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
Molecular Weight
Mass (kDA):
30.18 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (6361531..6370242) |
Tissue Specificity
Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.
Subcellular Localizations
Mitochondrion matrix.
Diseases
- Pneumonia
- Infective Disorder
- Salmonella Infections
- Physiological Stress
- Pneumococcal Infections
- Urinary Stress Incontinence
- Aortic Aneurysm, Abdominal
- Coughing
- Tuberculosis
- Urinary Incontinence
- Tissue Adhesions
- Systemic Infection
Pathways
- Proteolysis
- Virulence
- Translation
- Biofilm Formation
- Sporulation
- Protein Unfolding
- Secretion
- Dna Replication
- Pathogenesis
- Localization
- Transport
- Cell Cycle
- Cell Division
PTMs
- Cleavage
- Phosphorylation
- Oxidation
Research Areas
- Core ESC-Like Genes
- Lipid and Metabolism
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLPP
bosterbio.com/bosterbio-gene-info-cards/CLPP
References
PMID: 8543061 by Bross P., et al. Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene.
PMID: 19892738 by Xu G., et al. Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini.