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- Table of Contents
CLPX Antibodies
AND CLPX ELISA kits, CLPX Proteins
Many biological assays use antibodies to detect CLPX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLPX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLPX antibodies...
Designing a Western blot for CLPX? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CLPX Western Blot GuideCLPX Infographic by Boster Bio
All CLPX Products
Product
Figures
Specificity
Applications
Price
Anti-TWIST1/2 Antibody Picoband®
5 Citations
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00980-1
100 μg/vial
Cat # A00980-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01009-2
100 μg/vial
Cat # M01009-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01009-1
100 μg/vial
Cat # M01009-1
100 μg/vial
Anti-PNP Antibody Picoband® (monoclonal, 7G5)
1 Citations
Human
IF, IHC, ICC, WB
$370
Cat # M00988
100 μg/vial
Cat # M00988
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A00978-1
100 μg/vial
Cat # A00978-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01018-6
100 μg/vial
Cat # M01018-6
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00996-3
100 μg/vial
Cat # M00996-3
100 μg/vial
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01015-2
100 μg/vial
Cat # M01015-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00996-2
100 μg/vial
Cat # M00996-2
100 μg/vial
CLPX Overview
Facts about ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (CLPX)
ATP-dependent specificity part of the Clp protease complex. Targets specific substrates for degradation by the Clp complex (PubMed:11923310, PubMed:22710082).
Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding action of TFAM and is necessary for maintaining a typical mitochondrial nucleoid structure (PubMed:22841477).
Gene Information
| Human | |
|---|---|
| Gene Name: | CLPX |
| Uniprot: | O76031 |
| Entrez: | 10845 |
Family
| Belongs to: |
|---|
| ClpX chaperone family |
Alternative Names
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial; ClpX caseinolytic peptidase X homolog (E. coli); ClpX caseinolytic protease X homolog; energy-dependent regulator of proteolysis
Molecular Weight
Mass (kDA):
69.224 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q22.31 |
| Sequence: | 15; NC_000015.10 (65148219..65185374, complement) |
Tissue Specificity
Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Subcellular Localizations
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Diseases
- Aortic Aneurysm, Abdominal
- Pneumonia
- Infective Disorder
- Salmonella Infections
- Abscess
- Hemolysis (disorder)
- Lyme Disease
- Suppressor Mutation
- Physiological Stress
- Cancer Patients And Suicide And Depression
- Tuberculosis
- Skin Diseases, Bacterial
Pathways
- Proteolysis
- Virulence
- Dna Replication
- Translation
- Protein Unfolding
- Cell Cycle
- Transposition
- Cell Division
- Sporulation
- Biofilm Formation
- Localization
- Pathogenesis
- Transport
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLPX
bosterbio.com/bosterbio-gene-info-cards/CLPX
References
PMID: 11003706 by Corydon T.J., et al. Human and mouse mitochondrial orthologs of bacterial ClpX.
PMID: 11923310 by Kang S.G., et al. Functional proteolytic complexes of the human mitochondrial ATP- dependent protease, hClpXP.