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May have its own peroxidase activity through its N-terminal peroxidase-like domainname. .
|Sequence:||15; NC_000015.10 (45092650..45114172, complement)|
Expressed in colon, small intestine, duodenum and tracheal surface epithelial cells (at protein level). Expressed in thyrocytes. Also detected in kidney, liver, lung, pancreas, prostate, salivary glands, rectum and testis.
Apical cell membrane; Multi-pass membrane protein. Cell junction. Localizes to the apical membrane of epithelial cells. Localizes on internal membrane structures under resting conditions, translocates to the plasma membrane and cell-cell junctions upon challenge with enteric pathogens, such as Escherichia coli.