EDC4 Antibodies

AND EDC4 ELISA kits, EDC4 Proteins

Many biological assays use antibodies to detect EDC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDC4 antibodies...

We validate the specificity of these antibodies to EDC4 by testing them on tissues known to express EDC4 positively and negatively. Browse below to find the EDC4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDC4 Infographic by Boster Bio

All EDC4 Products

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Anti-EDC4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05173
100ul

Anti-EDC4 Antibody Picoband®

Western blot analysis of EDC4 using anti-EDC4 antibody (A05173-2)

IHC analysis of EDC4 using anti-EDC4 antibody (A05173-2)

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A05173-2
100 μg/vial

EDC4 Overview

Facts about Enhancer of mRNA-decapping protein 4.

EDC4 3D structure. Source: alphafold

Enhancer of mRNA-decapping protein 4 (EDC4)

In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A that functions in decapping of ARE-containing mRNAs.

Promotes complex formation between DCP1A and DCP2. Enhances the catalytic action of DCP2 (in vitro).

Gene Information

Human
Gene Name:	EDC4
Uniprot:	Q6P2E9
Entrez:	23644

Family

Belongs to:

WD repeat EDC4 family

Alternative Names

Autoantigen Ge-1; Autoantigen RCD-8; enhancer of mRNA decapping 4; enhancer of mRNA-decapping protein 4; Ge-1; Hedls; HEDLSHuman enhancer of decapping large subunit; RCD-8

Molecular Weight

Mass (kDA):
151.661 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (67873052..67884499)

Subcellular Localizations

Cytoplasm, P-body. Nucleus.

Diseases

Autoimmune Diseases
Biliary Cirrhosis
Primary Biliary Cirrhosis
Autoimmune Reaction
Liver Cirrhosis
Sjogren's Syndrome
Flexed Fetal Attitude
Dystonia Disorders
Physiological Stress
Autoimmunity
Thoracic Outlet Syndrome
Ataxia

Cervical Rib
Lupus Erythematosus, Systemic
Rheumatoid Arthritis
Transient Ischemic Attack
Ulnar Neuropathies
Liver Carcinoma

Interacting Proteins

AGO3
COASY
DCP1A
DCP2
EIF2AK2

Pathways

Localization
Mrna Processing
Gene Silencing
Rna Interference
Response To Stress
Cell Proliferation

Rna Processing

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDC4

References

PMID: 7520377 by Bloch D.B., et al. The immunoreactive region in a novel autoantigen contains a nuclear localization sequence.

PMID: 9067524 by Garcia-Lozano J.R., et al. Cytoplasmic detection of a novel protein containing a nuclear localization sequence by human autoantibodies.