Protein EFR3 homolog A Antibodies

AND EFR3A ELISA kits, Protein EFR3 homolog A Proteins

Many biological assays use antibodies to detect Protein EFR3 homolog A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein EFR3 homolog A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein EFR3 homolog A antibodies...

We validate the specificity of these antibodies to Protein EFR3 homolog A by testing them on tissues known to express EFR3A positively and negatively. Browse below to find the EFR3A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EFR3A Infographic by Boster Bio

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EFR3A (NM_015137) Human Over-expression Lysate

Human

$628
Cat # LS023167
20 µg, 100 µg

EFR3A Overview

Facts about Protein EFR3 homolog A.

EFR3A 3D structure. Source: alphafold

Protein EFR3 homolog A (EFR3A)

Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) into the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable).

From the complex, EFR3A probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).

Gene Information

Human
Gene Name:	EFR3A
Uniprot:	Q14156
Entrez:	23167

Family

Belongs to:

EFR3 family

Alternative Names

DKFZp781J0562; EFR3 homolog A (S. cerevisiae); KIAA0143Protein EFR3-like; protein EFR3 homolog A

Molecular Weight

Mass (kDA):
92.924 kDA

Genomic Context


Human

Location:	8q24.22
Sequence:	8; NC_000008.11 (131904093..132013642)

Subcellular Localizations

Cell membrane; Lipid-anchor. Cytoplasm, cytosol. Palmitoylation anchors the protein to the plasma membrane (PubMed:23229899, PubMed:25380825, PubMed:26571211). A small amount is observed in the cytosol (PubMed:25380825).

PTMs

Lipoprotein

Palmitate

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EFR3A

References

PMID: 23229899 by Nakatsu F., et al. PtdIns4P synthesis by PI4KIIIalpha at the plasma membrane and its impact on plasma membrane identity.

PMID: 24860643 by Gupta A.R., et al. Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.