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- Table of Contents
EHD3 Antibodies
AND EHD3 ELISA kits, EHD3 Proteins
Many biological assays use antibodies to detect EHD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EHD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EHD3 antibodies...
Designing a Western blot for EHD3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EHD3 Western Blot GuideEHD3 Infographic by Boster Bio
All EHD3 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04576-1
100 μg/vial
Cat # A04576-1
100 μg/vial
EHD3 Overview
Facts about EH domain-containing protein 3.
EH domain-containing protein 3 (EHD3)
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). Binding to phosphatidic acid induces its membrane tubulation activity (By similarity).
Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport.
Gene Information
| Human | |
|---|---|
| Gene Name: | EHD3 |
| Uniprot: | Q9NZN3 |
| Entrez: | 30845 |
Family
| Belongs to: |
|---|
| TRAFAC class dynamin-like GTPase superfamily |
Alternative Names
EH domain containing 3; EH domain-containing protein 3; EHD2; EH-domain containing 3; PAST homolog 3; PAST3
Molecular Weight
Mass (kDA):
60.887 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.1 |
| Sequence: | 2; NC_000002.12 (31234152..31269451) |
Tissue Specificity
Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta.
Subcellular Localizations
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250). Colocalizes with RAB8A and MYO5B to a cytoplasmic tubular network devoid of RAB11A (By similarity). Colocalizes with ANK2 in myocyte perinuclear region (PubMed:20489164). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippoc
Diseases
- Cardiovascular Diseases
- Tissue Adhesions
- Disease Of Capillaries
- Diabetic Nephropathy
- Infarction
- Glioma
- Pre-eclampsia
- Malignant Neoplasm Of Lung
- Carcinogenesis
- Leukemia, Myelocytic, Acute
- Myocardial Infarction
- Edema
- Malignant Neoplasms
Interacting Proteins
- ANK2
- ANKFY1
- EHD1
- Ehd3
- MICALL1
Pathways
- Localization
- Endocytosis
- Endocytic Recycling
- Transport
- Cell Adhesion
- Transcytosis
- Cell Differentiation
- Receptor Recycling
- Clathrin-mediated Endocytosis
- Hexose Transport
- Protein Targeting
- Regulation Of Gene Expression
- Nuclear Export
PTMs
- Sumoylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EHD3
bosterbio.com/bosterbio-gene-info-cards/EHD3
References
PMID: 10673336 by Pohl U., et al. EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.
PMID: 12121420 by Galperin E., et al. EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.