GRB10-interacting GYF protein 2 (GIGYF2)

Key component of the 4EHP-GYF2 complicated, a multiprotein complex that functions as a repressor of translation initiation (PubMed:22751931). In 4EHP-GYF2 the complex, functions as a factor that bridges EIF4E2 into ZFP36/TTP, linking translation repression with mRNA decay (By similarity).

May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153). .