GLRA3 Antibodies

AND GLRA3 ELISA kits, GLRA3 Proteins

Many biological assays use antibodies to detect GLRA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GLRA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GLRA3 antibodies...

We validate the specificity of these antibodies to GLRA3 by testing them on tissues known to express GLRA3 positively and negatively. Browse below to find the GLRA3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GLRA3 Infographic by Boster Bio

All GLRA3 Products

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Specificity

Applications

Price

Glycine Receptor alpha 3 (GLRA3) (NM_006529) Human Over-expression Lysate

Human

$628
Cat # LS008001
20 µg, 100 µg

Anti-GLRA3 Antibody Picoband®

Western blot analysis of GLRA3 using anti-GLRA3 antibody (A09110-1)

Human

ELISA, WB

$370
Cat # A09110-1
100 μg/vial

GLRA3 Overview

Facts about Glycine receptor subunit alpha-3.

GLRA3 3D structure. Source: alphafold

Glycine receptor subunit alpha-3 (GLRA3)

Channel opening is triggered by extracellular glycine (PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition; heteropentameric channels display quicker channel closure (By similarity).

Plays an important role in the down-regulation of neuronal excitability (By similarity). Contributes to the generation of inhibitory postsynaptic currents (By similarity).

Gene Information

Human
Gene Name:	GLRA3
Uniprot:	O75311
Entrez:	8001

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

Glycine receptor subunit alpha-3

Molecular Weight

Mass (kDA):
53.8 kDA

Genomic Context


Human

Location:	4q34.1
Sequence:	4; NC_000004.12 (174636920..174829568, complement)

Tissue Specificity

Widely distributed throughout the central nervous system.

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Cell junction, synapse. Cell membrane; Multi-pass membrane protein. Partially colocalizes with GPHN that is known to mediate receptor clustering at postsynaptic membranes.

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GLRA3

References

PMID: 9677400 by Nikolic Z., et al. The human glycine receptor subunit alpha3. GLRA3 gene structure, chromosomal localization, and functional characterization of alternative transcripts.

PMID: 26416729 by Huang X., et al. Crystal structure of human glycine receptor-alpha3 bound to antagonist strychnine.