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- Table of Contents
GNB3 Antibodies
AND GNB3 ELISA kits, GNB3 Proteins
Many biological assays use antibodies to detect GNB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNB3 antibodies...
Designing a Western blot for GNB3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GNB3 Western Blot GuideGNB3 Infographic by Boster Bio
All GNB3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02407-2
100 μg/vial
Cat # A02407-2
100 μg/vial
GNB3 Overview
Facts about Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (GNB3)
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Gene Information
| Human | |
|---|---|
| Gene Name: | GNB3 |
| Uniprot: | P16520 |
| Entrez: | 2784 |
Family
| Belongs to: |
|---|
| WD repeat G protein beta family |
Alternative Names
G protein, beta-3 subunit; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; hypertension associated protein; Transducin beta chain 3
Molecular Weight
Mass (kDA):
37.221 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.31 |
| Sequence: | 12; NC_000012.12 (6840922..6847393) |
Diseases
- Hypertensive Disease
- Cholangiocarcinoma
- Obesity
- Essential Hypertension
- Diabetes Mellitus
- Cardiovascular Diseases
- Infarction
- Myocardial Infarction
- Diabetes Mellitus, Non-insulin-dependent
- Depressive Disorder
- Coronary Artery Disease
- Heart Diseases
Interacting Proteins
- CXCR5
Pathways
- Pathogenesis
- Intracellular Signal Transduction
- Vasoconstriction
- Excretion
- Transport
- Chemotaxis
- Vasodilation
- Platelet Aggregation
- Menopause
- Cell Activation
- Immune Response
- Platelet Activation
- Lymphocyte Chemotaxis
PTMs
- Methylation
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNB3
bosterbio.com/bosterbio-gene-info-cards/GNB3
References
PMID: 2107550 by Levine M.A., et al. Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide.
PMID: 8723724 by Ansari-Lari M.A., et al. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.