GPR84 Antibodies

AND GPR84 ELISA kits, GPR84 Proteins

Many biological assays use antibodies to detect GPR84, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR84 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR84 antibodies...

We validate the specificity of these antibodies to GPR84 by testing them on tissues known to express GPR84 positively and negatively. Browse below to find the GPR84 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR84 Infographic by Boster Bio

All GPR84 Products

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Price

Anti-G-protein coupled receptor 84 GPR84 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08963
100ul

GPR84 (NM_020370) Human Over-expression Lysate

Human

$628
Cat # LS053831
20 µg, 100 µg

GPR84 Overview

Facts about G-protein coupled receptor 84.

GPR84 3D structure. Source: alphafold

G-protein coupled receptor 84 (GPR84)

Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists.

Not triggered by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway.

Gene Information

Human
Gene Name:	GPR84
Uniprot:	Q9NQS5
Entrez:	53831

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

EX33; EX33Inflammation-related G-protein coupled receptor EX33; G protein-coupled receptor 84; GPCR4; GPR84; G-protein coupled receptor 84; inflammation-related G protein-coupled receptor EX33

Molecular Weight

Mass (kDA):
43.705 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (54362445..54365224, complement)

Tissue Specificity

Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Diabetes Mellitus
Inflammation
Diabetes Mellitus, Non-insulin-dependent
Obesity
Insulin Resistance
Metabolic Diseases
Pertussis
Sclerosis
Dyslipidemias
Chronic Inflammation
Inflammatory Bowel Diseases
Multiple Sclerosis
Encephalomyelitis

Tissue Adhesions
Insulin Sensitivity
Experimental Autoimmune Encephalomyelitis
Intestinal Diseases
Corneal Diseases
Autoimmune Reaction
Chronic Active Inflammation

Pathways

Gastric Motility
Cell Proliferation
Fermentation
Insulin Secretion
Regulation Of Appetite
Pathogenesis
Energy Homeostasis
Eye Development

Localization
Neutrophil Activation
Secretion

PTMs

Glycoprotein

Phosphoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR84

References

PMID: 11404393 by Yousefi S., et al. Cloning and expression analysis of a novel G-protein-coupled receptor selectively expressed on granulocytes.

PMID: 11273702 by Wittenberger T., et al. An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors.