Glutathione peroxidase 2 Antibodies

AND GPX2 ELISA kits, Glutathione peroxidase 2 Proteins

Many biological assays use antibodies to detect Glutathione peroxidase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glutathione peroxidase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glutathione peroxidase 2 antibodies...

We validate the specificity of these antibodies to Glutathione peroxidase 2 by testing them on tissues known to express GPX2 positively and negatively. Browse below to find the GPX2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPX2 Infographic by Boster Bio

All GPX2 Products

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Specificity

Applications

Price

Anti-Glutathione peroxidase 2 GPX2 Antibody

Western blot analysis of extracts of various cell lines, using GPX2 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded human colon carcinoma using GPX2 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat stomach using GPX2 antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A03837
100ul

Human Glutathione Peroxidase 2 (u40C) Recombinant Protein

SDS-PAGE

$350
Cat # PROTP18283
Starting from 10ug

Anti-Glutathione Peroxidase 2 Rabbit Monoclonal Antibody

Western blot analysis of GPX2 using anti-GPX2 antibody (M03837)

Human

IHC, WB

$370
Cat # M03837
100 μl/vial

Glutathione Peroxidase 2 (GPX2) (NM_002083) Human Over-expression Lysate

Human

$628
Cat # LS002877
20 µg, 100 µg

GPX2 Overview

Facts about Glutathione peroxidase 2.

Glutathione peroxidase 2 (GPX2)

Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide although not phosphatidycholine hydroperoxide, can act as acceptors.

Gene Information

Human
Gene Name:	GPX2
Uniprot:	P18283
Entrez:	2877

Family

Belongs to:

glutathione peroxidase family

Alternative Names

EC 1.11.1; EC 1.11.1.9; gastrointestinal glutathione peroxidase 2; Gastrointestinal glutathione peroxidase; GIGPX; GI-GPx; glutathione peroxidase 2 (gastrointestinal); Glutathione Peroxidase 2; Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPX2; GPx-2; GPx-GI; GSHPx-2; GSHPX-GI

Molecular Weight

Mass (kDA):
21.954 kDA

Genomic Context


Human

Location:	14q23.3
Sequence:	14; NC_000014.9 (64939158..64942745, complement)

Tissue Specificity

Mostly in liver and gastrointestinal tract, not found in heart or kidney.

Subcellular Localizations

Cytoplasm. Mainly cytoplasmic.

Diseases

Malignant Neoplasms
Neoplasms
Inflammation
Hepatocarcinogenesis
Carcinogenesis
Liver Neoplasms, Experimental
Malignant Tumor Of Colon
Cell Transformation, Neoplastic
Iieocolitis
Colitis
Adenocarcinoma
Carcinoma

Colorectal Cancer
Inflammatory Bowel Diseases
Crohn Disease
Liver Neoplasms
Colonic Neoplasms
Colorectal Neoplasms

Pathways

Cell Proliferation
Localization
Cell Cycle
Pathogenesis
Response To Stress
Cell Death
Cell Growth
Transport
Aging
Response To Oxidative Stress
Protein Oxidation
Regeneration
Dna Hypermethylation

Gene Silencing
Selenocysteine Incorporation
Photosynthesis
Immune Response
Lung Development
Peroxidase Reaction
Neurogenesis

PTMs

Reduction
Oxidation

Nitrosylation
Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPX2

References

PMID: 2388849 by Akasaka M., et al. A human cDNA sequence of a novel glutathione peroxidase-related protein.

PMID: 8428933 by Chu F.-F., et al. Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI.