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- Table of Contents
GSTA4 Antibodies
AND GSTA4 ELISA kits, GSTA4 Proteins
Many biological assays use antibodies to detect GSTA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GSTA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GSTA4 antibodies...
Designing a Western blot for GSTA4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GSTA4 Western Blot GuideGSTA4 Infographic by Boster Bio
All GSTA4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # PB9627
100 μg/vial
Cat # PB9627
100 μg/vial
Human, Monkey
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03699-1
100 μg/vial
Cat # A03699-1
100 μg/vial
GSTA4 Overview
Facts about Glutathione S-transferase A4.
Glutathione S-transferase A4 (GSTA4)
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | GSTA4 |
| Uniprot: | O15217 |
| Entrez: | 2941 |
Family
| Belongs to: |
|---|
| GST superfamily |
Alternative Names
DKFZp686D21185; EC 2.5.1.18; glutathione S-alkyltransferase A4; glutathione S-aralkyltransferase A4; glutathione S-aryltransferase A4; glutathione S-transferase A4; Glutathione S-transferase A4-4; glutathione S-transferase alpha 4; glutathione transferase A4-4; GST class-alpha member 4; GSTA4-4; GTA4; S-(hydroxyalkyl)glutathione lyase A4
Molecular Weight
Mass (kDA):
25.704 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p12.2 |
| Sequence: | 6; NC_000006.12 (52977952..52995332, complement) |
Tissue Specificity
Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver.
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Carcinogenesis
- Carcinoma
- Neoplasms
- Liver Carcinoma
- Adenoma
- Adenocarcinoma
- Insulin Resistance
- Obesity
- Malignant Tumor Of Colon
- Malignant Paraganglionic Neoplasm
- Infarction
Interacting Proteins
- C2orf50
- GSTA2
Pathways
- Fermentation
- Transport
- Cell Cycle
- Conjugation
- Methylation
- Regeneration
- Pathogenesis
- Dna Hypermethylation
- Aging
- Glucose Transport
- Cell Proliferation
- Dna Methylation
- Localization
PTMs
- Phosphorylation
- Methylation
- Glutathionylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GSTA4
bosterbio.com/bosterbio-gene-info-cards/GSTA4
References
PMID: 9461507 by Hubatsch I., et al. Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation.
PMID: 9480897 by Board P.G.; Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.