H2BC4 Antibodies

AND H2BC4 ELISA kits, H2BC4 Proteins

Many biological assays use antibodies to detect H2BC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with H2BC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop H2BC4 antibodies...

We validate the specificity of these antibodies to H2BC4 by testing them on tissues known to express H2BC4 positively and negatively. Browse below to find the H2BC4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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H2BC4 Infographic by Boster Bio

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H2BC4 (NM_003526) Human Over-expression Lysate

Human

$628
Cat # LS008347
20 µg, 100 µg

H2BC4 Overview

Facts about Histone H2B type 1-C/E/F/G/I.

H2BC4 3D structure. Source: alphafold

Histone H2B type 1-C/E/F/G/I (H2BC4)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Information

Human
Gene Name:	H2BC4
Uniprot:	P62807
Entrez:	8347

Family

Belongs to:

histone H2B family

Alternative Names

Histone H2B type 1-C/E/F/G/I

Molecular Weight

Mass (kDA):
13.906 kDA

Genomic Context


Human

Location:	6p22.2
Sequence:	6; NC_000006.12 (26123467..26123926, complement)

Subcellular Localizations

Nucleus. Chromosome.

Interacting Proteins

AP2M1
H2AFB2

PTMs

Acetylation
Glycoprotein
Hydroxylation

Isopeptide bond
Methylation
Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/H2BC4

References

PMID: 1916825 by Albig W., et al. Isolation and characterization of two human H1 histone genes within clusters of core histone genes.

PMID: 9119399 by Albig W., et al. Human histone gene organization: nonregular arrangement within a large cluster.