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- Table of Contents
Laminin subunit alpha-4 Antibodies
AND LAMA4 ELISA kits, Laminin subunit alpha-4 Proteins
Many biological assays use antibodies to detect Laminin subunit alpha-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Laminin subunit alpha-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Laminin subunit alpha-4 antibodies...
Designing an IHC experiment for Laminin subunit alpha-4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LAMA4 IHC GuideLAMA4 Infographic by Boster Bio
All LAMA4 Products
Product
Figures
Specificity
Applications
Price
Human
$960
Cat # LS003910
20 µg, 100 µg
Cat # LS003910
20 µg, 100 µg
LAMA4 Overview
Facts about Laminin subunit alpha-4.
Laminin subunit alpha-4 (LAMA4)
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LAMA4 |
| Uniprot: | Q16363 |
| Entrez: | 3910 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DKFZp686D23145; LAMA3LAMA4*-1; LAMA4; laminin alpha 4 chain; Laminin alpha 4; laminin subunit alpha-4; laminin, alpha 4; Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha
Molecular Weight
Mass (kDA):
202.524 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q21 |
| Sequence: | 6; NC_000006.12 (112107931..112254722, complement) |
Tissue Specificity
In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
Diseases
- Tissue Adhesions
- Tumor Angiogenesis
- Neoplasms
- Neoplasm Metastasis
- Cell Invasion
- Neoplasm Invasiveness
- Carcinoma
- Dystrophy
- Cardiomyopathies
- Muscular Dystrophy
- Malignant Neoplasms
- Congenital Muscular Dystrophy (disorder)
- Fibrosis
Interacting Proteins
- TP53
Pathways
- Cell Adhesion
- Angiogenesis
- Localization
- Cell Proliferation
- Regeneration
- Cell Migration
- Immune Response
- Myelination
- Secretion
- Proteolysis
- Reverse Transcription
- Translation
- Cell Cycle
PTMs
- Glycosylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAMA4
bosterbio.com/bosterbio-gene-info-cards/LAMA4
References
PMID: 7781776 by Iivanainen A., et al. Primary structure and expression of a novel human laminin alpha 4 chain.
PMID: 8706685 by Richards A.J., et al. The complete cDNA sequence of laminin alpha 4 and its relationship to the other human laminin alpha chains.