Cation-dependent mannose-6-phosphate receptor (M6PR)

Transport of phosphorylated lysosomal enzymes in the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the consequent receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.